DEHYDROABIETYLAMINE
- CAS No.
- 1446-61-3
- Chemical Name:
- DEHYDROABIETYLAMINE
- Synonyms
- Leelamine;AMINE D;DEHYDROABIETHYLAMINE;((1R,4aS,10aR)-7-Isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine;NSC 2955;55.0%(GC);Leelamine HCl;((1R,4aS,10aR);Water galbanum;Dehydrobietylamine
- CBNumber:
- CB1692875
- Molecular Formula:
- C20H31N
- Molecular Weight:
- 285.47
- MDL Number:
- MFCD06795849
- MOL File:
- 1446-61-3.mol
- MSDS File:
- SDS
Melting point | 44.50℃ |
---|---|
Boiling point | 417.89°C (rough estimate) |
Density | 0.963±0.06 g/cm3 (20 ºC 760 Torr) |
refractive index |
n |
Flash point | >230 °F |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | Chloroform, DMSO, Methanol |
form | White solid. |
pka | 10.13±0.29(Predicted) |
color | Pale Yellow |
optical activity | [α]20/D +56.1°, c = 2.4 in pyridine |
BRN | 3084620 |
CAS DataBase Reference | 1446-61-3(CAS DataBase Reference) |
FDA UNII | 33289O147P |
EPA Substance Registry System | Dehydroabietylamine (1446-61-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | TP8701000 | |||||||||
F | 10-23 | |||||||||
HS Code | 29214990 | |||||||||
Hazardous Substances Data | 1446-61-3(Hazardous Substances Data) | |||||||||
NFPA 704 |
|
DEHYDROABIETYLAMINE price More Price(29)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 105198 | (+)-Dehydroabietylamine technical grade, 60% | 1446-61-3 | 100g | $48.4 | 2024-03-01 | Buy |
TCI Chemical | D1588 | (+)-Dehydroabietylamine [Optical Resolving Agent] >90.0%(GC) | 1446-61-3 | 5g | $94 | 2024-03-01 | Buy |
TCI Chemical | D1180 | Dehydroabietylamine min. 55.0 % | 1446-61-3 | 25G | $36 | 2024-03-01 | Buy |
TCI Chemical | D1588 | (+)-Dehydroabietylamine [Optical Resolving Agent] >90.0%(GC) | 1446-61-3 | 25g | $282 | 2024-03-01 | Buy |
Cayman Chemical | 10006148 | Leelamine ≥98% | 1446-61-3 | 5mg | $37 | 2024-03-01 | Buy |
DEHYDROABIETYLAMINE Chemical Properties,Uses,Production
Chemical Properties
clear yellow viscous liquid
Uses
Dehydroabiethylamine is a primary amine with high molecular weight; shows a strong antibiotic effect with a broad spectrum of activity against Staphylococcus p.a. (sic), Escherichia coli, Mycobacterium tuberculosis, and Candida albicans.
Definition
ChEBI: [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine is a diterpenoid.
Biological Activity
CB 1 agonist. Displaces binding of [ 3 H]-SR141716A with an IC 50 value of 2.86 μ M.
Purification Methods
The crude base is purified by converting 2g of base in toluene (3.3mL) into the acetate salt by heating at 65-70o with 0.46g of AcOH, and the crystals are collected and dried (0.96g from two crops, m 141-143o). The acetate salt is dissolved in warm H2O, basified with aqueous NaOH and extracted with *C6H6. The dried extract (MgSO4) is evaporated in vacuum leaving a viscous oil which crystallises and can be distilled. [Gottstein & Cheney J Org Chem 30 2072 1965.] The picrate has m 234-236o (from aqueous MeOH), and the formate has m 147-148o (from heptane). [Beilstein 12 IV 3005.]
DEHYDROABIETYLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from DEHYDROABIETYLAMINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-19 | Dehydroabiethylamine
1446-61-3
|
US $29.00 / mL | 97.24% | 10g | TargetMol Chemicals Inc. | |||
2022-05-23 | DEHYDROABIETYLAMINE
1446-61-3
|
US $2550.00 / ml | 1ml | ≥90% | 10 kgs | GLR Innovations | ||
2021-10-29 | (+)-Dehydroabiethylamine
1446-61-3
|
US $0.00 / ASSAYS | 100ASSAYS | 99.99% | 10000 | Jiangsu Monade Biological Technology Co., Ltd. |
- Dehydroabiethylamine
1446-61-3
- US $29.00 / mL
- 97.24%
- TargetMol Chemicals Inc.
- DEHYDROABIETYLAMINE
1446-61-3
- US $2550.00 / ml
- ≥90%
- GLR Innovations
- (+)-Dehydroabiethylamine
1446-61-3
- US $0.00 / ASSAYS
- 99.99%
- Jiangsu Monade Biological Technology Co., Ltd.
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