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DEHYDROABIETYLAMINE

CAS No.
1446-61-3
Chemical Name:
DEHYDROABIETYLAMINE
Synonyms
Leelamine;AMINE D;DEHYDROABIETHYLAMINE;((1R,4aS,10aR)-7-Isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine;NSC 2955;55.0%(GC);Leelamine HCl;((1R,4aS,10aR);Water galbanum;Dehydrobietylamine
CBNumber:
CB1692875
Molecular Formula:
C20H31N
Molecular Weight:
285.47
MDL Number:
MFCD06795849
MOL File:
1446-61-3.mol
MSDS File:
SDS
Last updated:2024-12-18 14:07:02

DEHYDROABIETYLAMINE Properties

Melting point 44.50℃
Boiling point 417.89°C (rough estimate)
Density 0.963±0.06 g/cm3 (20 ºC 760 Torr)
refractive index n20/D 1.546(lit.)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform, DMSO, Methanol
form White solid.
pka 10.13±0.29(Predicted)
color Pale Yellow
optical activity [α]20/D +56.1°, c = 2.4 in pyridine
BRN 3084620
CAS DataBase Reference 1446-61-3(CAS DataBase Reference)
FDA UNII 33289O147P
EPA Substance Registry System Dehydroabietylamine (1446-61-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  TP8701000
10-23
HS Code  29214990
Hazardous Substances Data 1446-61-3(Hazardous Substances Data)
NFPA 704
1
2 0

DEHYDROABIETYLAMINE price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 105198 (+)-Dehydroabietylamine technical grade, 60% 1446-61-3 100g $48.4 2024-03-01 Buy
TCI Chemical D1588 (+)-Dehydroabietylamine [Optical Resolving Agent] >90.0%(GC) 1446-61-3 5g $94 2024-03-01 Buy
TCI Chemical D1180 Dehydroabietylamine min. 55.0 % 1446-61-3 25G $36 2024-03-01 Buy
TCI Chemical D1588 (+)-Dehydroabietylamine [Optical Resolving Agent] >90.0%(GC) 1446-61-3 25g $282 2024-03-01 Buy
Cayman Chemical 10006148 Leelamine ≥98% 1446-61-3 5mg $37 2024-03-01 Buy
Product number Packaging Price Buy
105198 100g $48.4 Buy
D1588 5g $94 Buy
D1180 25G $36 Buy
D1588 25g $282 Buy
10006148 5mg $37 Buy

DEHYDROABIETYLAMINE Chemical Properties,Uses,Production

Chemical Properties

clear yellow viscous liquid

Uses

Dehydroabiethylamine is a primary amine with high molecular weight; shows a strong antibiotic effect with a broad spectrum of activity against Staphylococcus p.a. (sic), Escherichia coli, Mycobacterium tuberculosis, and Candida albicans.

Definition

ChEBI: [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine is a diterpenoid.

Biological Activity

CB 1 agonist. Displaces binding of [ 3 H]-SR141716A with an IC 50 value of 2.86 μ M.

Purification Methods

The crude base is purified by converting 2g of base in toluene (3.3mL) into the acetate salt by heating at 65-70o with 0.46g of AcOH, and the crystals are collected and dried (0.96g from two crops, m 141-143o). The acetate salt is dissolved in warm H2O, basified with aqueous NaOH and extracted with *C6H6. The dried extract (MgSO4) is evaporated in vacuum leaving a viscous oil which crystallises and can be distilled. [Gottstein & Cheney J Org Chem 30 2072 1965.] The picrate has m 234-236o (from aqueous MeOH), and the formate has m 147-148o (from heptane). [Beilstein 12 IV 3005.]

35928-32-6
1446-61-3
Synthesis of DEHYDROABIETYLAMINE from DEHYDROABIETYLAMINE

DEHYDROABIETYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 235)Suppliers
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Capot Chemical Co.,Ltd.
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SIMAGCHEM CORP
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TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
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+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from DEHYDROABIETYLAMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dehydroabiethylamine pictures 2024-11-19 Dehydroabiethylamine
1446-61-3
US $29.00 / mL 97.24% 10g TargetMol Chemicals Inc.
DEHYDROABIETYLAMINE pictures 2022-05-23 DEHYDROABIETYLAMINE
1446-61-3
US $2550.00 / ml 1ml ≥90% 10 kgs GLR Innovations
(+)-Dehydroabiethylamine pictures 2021-10-29 (+)-Dehydroabiethylamine
1446-61-3
US $0.00 / ASSAYS 100ASSAYS 99.99% 10000 Jiangsu Monade Biological Technology Co., Ltd.
(+)-DEHYDROABIETYLAMINE DEHYDROABIETYLAMINE (+)-DEHYDROABIETHYLAMINE D(+)-DEHYDROABIETYLAMINE 1-Phenanthrenemethanamine, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)- 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1.alpha.,4a.beta.,10a.alpha.)]1-Phenanthrenemethanamine (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl-1-phenanthrenemethanamine) NSC 2955 1-phenanthrenemethanamine,1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-met Dehydrobietylamine (1R)-(1,2,3,4,4a,9,10,10aα-Octahydro-7-isopropyl-1,4aβ-dimethylphenanthrene)-1α-methanamine (1R)-1,2,3,4,4a,9,10,10aα-Octahydro-1,4aβ-dimethyl-7-(1-methylethyl)-1α-phenanthrenemethanamine (1R)-1,2,3,4,4a,9,10,10aα-Octahydro-1,4aβ-dimethyl-7-(1-methylethyl)phenanthrene-1α-methanamine (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-isopropyl-1-phenanthrenemethanamine Dehydroabietylamine,60%,tech. Dehydroabietylamine1,4a-Dimethyl-7-isopropyl-1,2,3,4,4a,9,10,10a-octahydro-1- phenanthrenemethylamine (d)-dehyroabiethylamine Leelamine hydrochloride DEHYDROABIETYLAMINE, TECH., 60% DehydroabietylamineTech60% LYLAMINE HYDROCHLORIDE (1R,4AS,10AR)-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-,4A-DIMETHYL-7-(1-METHYLETHYL)-1-PHENANTHRENEMETHANAMINE HYDROCHLORIDE 1,4A-DIMETHYL-7-ISOPROPYL-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-PHENANTHRENEMETHYLAMINE 1 4A-DIMETHYL-7-ISOPROPYL-1 2 3,4A 9 10 10A-OCTAHYDRO-1-PHENANTHRENE METHYLAMINE (1r-(1alpha,4abeta,10aalpha))-hylethyl) [1theta-(1alpha,4abeta,10aalpha)]-hylethyl) 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-,[1R-(1.alpha.,4a.beta.,10a.alpha.)]1-Phenanthrenemethanamine 13-isopropylpodocarpa-8,11,13-trien-15-amine 13-trien-15-amine,13-isopropyl-podocarpa-11 (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine ,60% ((1S,4aS,10aR)-7-isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine (+)DehyroabietylaMine (1R,4aS,10aR)-1-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-phenanthrenemethanamine DehydroabiethylaMine (>80%) (+)-Dehydroabietylamine technical grade, 60% Leelamine HCl (+)-Dehydroabietylamine  [Optical Resolving Agent] ((1R,4aS,10aR) -7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl) (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4adimethyl- 7-(1-methylethyl)-1-phenanthrenemethanamine,99%d.e. (+)-Dehydroabietylamine Leelamine free base (+)-Dehydroabietylamine[OpticalResolvingAgent]> 55.0%(GC) Dehydroabietylamine > (+)-Dehydroabietylamine [Optical Resolving Agent] (+)-Dehydroabiethylamine 1446-61-3 C20H31N DEHYDROABIETYLAMINE DEHYDROABIETHYLAMINE AMINE D Leelamine ((1R,4aS,10aR)-7-Isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine Pyruvate dehydrogenase kinase,PDH kinase,Dehydroabiethylamine,Inhibitor,PDHK,Cannabinoid Receptor,inhibit Water galbanum 1446-61-3 C20H31N C20H31NHCl