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SE 175

SE 175 Structure
SE 175 structure
CAS No.
258278-64-7
Chemical Name:
SE 175
Synonyms
SE 175;SE 175 >=97%;NO PRODRUG, SE 175;JDIVRBDMTYQVOK-UHFFFAOYSA-N;S-(4-NITROOXYMETHYLBENZOYL)METHYLTHIOSALICYLATE;2-[[4-[(NITROOXY)METHYL]BENZOYL]THIO]-BENZOIC ACID, METHYL ESTER;Benzoic acid, 2-[[4-[(nitrooxy)methyl]benzoyl]thio]-, methyl ester
CBNumber:
CB1732391
Molecular Formula:
C16H13NO6S
Molecular Weight:
347.34
MDL Number:
MFCD03412030
MOL File:
258278-64-7.mol
Last updated:2023-04-23 13:52:06
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SE 175 Properties

Boiling point 493.8±45.0 °C(Predicted)
Density 1.40±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMF:50.0(Max Conc. mg/mL);143.53(Max Conc. mM)
DMSO:35.0(Max Conc. mg/mL);100.47(Max Conc. mM)
Ethanol:11.0(Max Conc. mg/mL);31.58(Max Conc. mM)
form A crystalline solid

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

SE 175 price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S2189 SE 175 ≥97% 258278-64-7 10mg $187 2024-03-01 Buy
Cayman Chemical 82340 SE 175 ≥97% 258278-64-7 5mg $59 2024-03-01 Buy
Cayman Chemical 82340 SE 175 ≥97% 258278-64-7 10mg $108 2024-03-01 Buy
Cayman Chemical 82340 SE 175 ≥97% 258278-64-7 50mg $448 2024-03-01 Buy
Cayman Chemical 82340 SE 175 ≥97% 258278-64-7 100mg $783 2024-03-01 Buy
Product number Packaging Price Buy
S2189 10mg $187 Buy
82340 5mg $59 Buy
82340 10mg $108 Buy
82340 50mg $448 Buy
82340 100mg $783 Buy

SE 175 Chemical Properties,Uses,Production

Description

SE 175 is an organic nitrate compound of the same general class as nitroglycerin. These nitrate compounds can act as NO-donors in vivo following reductive transformation of the nitrate group to nitric oxide. The nitroxyacylated thiosalicylates, such as SE 175, were developed in an effort to facilitate this reductive process and accelerate the release of NO. SE 175 is stable in buffer or saline solution. In the intact rat, it stimulates endothelial soluble guanylate cyclase and induces aortic vasorelaxation with an EC50 of 20 μM, which is intermediate in potency between nitroglycerine and isosorbide dinitrate.

SE 175 Preparation Products And Raw materials

Raw materials

Preparation Products

SE 175 Suppliers

Global( 25)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44918 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 8041 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
ApexBio Technology -- sales@apexbt.com United States 6251 58
Supplier Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
Energy Chemical 58
Nanjing Tengyi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
ApexBio Technology 58

258278-64-7(SE 175)Related Search:

SE 175 2-[(4-METHYLBENZYL)SULFANYL]BENZENECARBOXYLIC ACID
2-[[4-[(NITROOXY)METHYL]BENZOYL]THIO]-BENZOIC ACID, METHYL ESTER NO PRODRUG, SE 175 S-(4-NITROOXYMETHYLBENZOYL)METHYLTHIOSALICYLATE SE 175 JDIVRBDMTYQVOK-UHFFFAOYSA-N Benzoic acid, 2-[[4-[(nitrooxy)methyl]benzoyl]thio]-, methyl ester SE 175 >=97% 258278-64-7 Substrates by Enzyme Nitric Oxide Synthase/NO Donor BioChemical Biochemicals and Reagents Enzyme Substrates Enzymes, Inhibitors, and Substrates Nitric Oxide DonorsEnzyme Substrates Nitric Oxide Synthase/NO Donor Nitric Oxide and Cell Stress Nitric Oxide Metabolism Substrates by Enzyme