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2-Bromothiazole

2-Bromothiazole Structure
2-Bromothiazole structure
CAS No.
3034-53-5
Chemical Name:
2-Bromothiazole
Synonyms
2-BROMO-1,3-THIAZOLE;CL028;TZ-Br;NSC 91532;2-Bromthiazol;2-bromo-thiazol;2-BROMOTHIAZOLE;2-BROMOTHIOAZOLE;Thiazole, 2-bromo-;2-THIAZOLYL BROMIDE
CBNumber:
CB1739860
Molecular Formula:
C3H2BrNS
Molecular Weight:
164.02
MDL Number:
MFCD00005316
MOL File:
3034-53-5.mol
MSDS File:
SDS
Last updated:2024-07-22 17:51:23
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2-Bromothiazole Properties

Melting point 171 C
Boiling point 171 °C (lit.)
Density 1.82 g/mL at 25 °C (lit.)
refractive index n20/D 1.593(lit.)
Flash point 146 °F
storage temp. 2-8°C
solubility Chloroform, Dichloromethane
pka 0.84±0.10(Predicted)
form Liquid
color Clear colorless to orange-brown
Specific Gravity 1.836
Water Solubility insoluble
BRN 105724
InChIKey RXNZFHIEDZEUQM-UHFFFAOYSA-N
CAS DataBase Reference 3034-53-5(CAS DataBase Reference)
FDA UNII 53KY5HU6FR
NIST Chemistry Reference Thiazole, 2-bromo-(3034-53-5)
EPA Substance Registry System Thiazole, 2-bromo- (3034-53-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H227-H315-H319-H335
Precautionary statements  P210e-P261-P280a-P305+P351+P338-P405-P501a-P210-P280-P403+P235-P501
Hazard Codes  Xi,F
Risk Statements  36/37/38
Safety Statements  23-24/25-36-26
RIDADR  1993
WGK Germany  3
TSCA  Yes
HazardClass  IRRITANT, FLAMMABLE
HS Code  29341000
NFPA 704
1
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2-Bromothiazole price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 160474 2-Bromothiazole 98% 3034-53-5 5g $54.9 2024-03-01 Buy
Sigma-Aldrich 160474 2-Bromothiazole 98% 3034-53-5 25g $102 2024-03-01 Buy
TCI Chemical B1280 2-Bromothiazole >98.0%(GC) 3034-53-5 25g $79 2024-03-01 Buy
TCI Chemical B1280 2-Bromothiazole >98.0%(GC) 3034-53-5 250g $464 2024-03-01 Buy
Alfa Aesar A14838 2-Bromothiazole, 99% 3034-53-5 10g $59.65 2024-03-01 Buy
Product number Packaging Price Buy
160474 5g $54.9 Buy
160474 25g $102 Buy
B1280 25g $79 Buy
B1280 250g $464 Buy
A14838 10g $59.65 Buy

2-Bromothiazole Chemical Properties,Uses,Production

Description

It is usually used as the intermediate or raw material to produce various products in the organic synthesis and pharmaceutical industry, such as 2-acetylthiazole, antibiotics, and anticholinergic drugs. Specifically, this chemical can act as the raw material to produce camalexin through reaction with indolylmagnesium iodide.1 Moreover, this substance has been selected as the reactant to prepare the thiazole Grignard reagents and thiazolyllithium compounds, which can be converted into thiazole-2-carboxylic acid via a halogen-metal exchange reaction.2, 3 In addition, 2-bromothiazole has been used to synthesize N-aryl aminothiazoles, which are found to function as the inhibitors of cyclin-dependent kinases.4 Besides, this compound may be involved in the synthesis of ethynylthiazoles that exhibits a desirable anti-inflammatory activity.5

Referrence

  1. Ayer, W. A.; Craw, P. A.; Ma, Y. T.; Miao, S. C., SYNTHESIS OF CAMALEXIN AND RELATED PHYTOALEXINS. Tetrahedron 1992, 48, 2919-2924.
  2. Kurkjy, R. P.; Brown, E. V., THE PREPARATION OF THIAZOLE GRIGNARD REAGENTS AND THIAZOLYLLITHIUM COMPOUNDS. J. Am. Chem. Soc. 1952, 74, 6260-6262.
  3. Beyerman, H. C.; Berben, P. H.; Bontekoe, J. S., THE SYNTHESIS OF THIAZOLE-2-CARBOXYLIC AND OF THIAZOLE-5-CARBOXYLIC ACID VIA A HALOGEN-METAL EXCHANGE REACTION. Recl. Trav. Chim. Pays-Bas-J. Roy. Neth. Chem. Soc. 1954, 73, 325-332.
  4. Misra, R. N.; Xiao, H. Y.; Williams, D. K.; Kim, K. S.; Lu, S. F.; Keller, K. A.; Mulheron, J. G.; Batorsky, R.; Tokarski, J. S.; Sack, J. S.; Kimball, D.; Lee, F. Y.; Webster, K. R., Synthesis and biological activity of N-aryl-2-aminothiazoles: potent pan inhibitors of cyclin-dependent kinases. Bioorg. Med. Chem. Lett. 2004, 14, 2973-2977.
  5. Geronikaki, A.; Vasilevsky, S.; Hadjipavlou-Litina, D.; Lagunin, A.; Poroikov, B. V., Synthesis and anti-inflammatory activity of ethynylthiazoles. Khim. Geterotsiklicheskikh Soedin. 2006, 769-774.

Chemical Properties

Colourless Liquid

Uses

2-Bromothiazole, is intended used for research purpose only. It is also used as Aryl halide which are used to N-arylate 5- and 7-azaindoles. Copper-catalyzed cyanation provides 2-cyanothiazole

Uses

2-Bromothiazole is a heterocyclic S compound to induce base-pair substitution and having mutagenic activity.

Uses

Aryl halide used to N-arylate 5- and 7-azaindoles.1 Copper-catalyzed cyanation provides 2-cyanothiazole.2

2-Bromothiazole Preparation Products And Raw materials

Raw materials

Phosphoric acid Nitric acid

Preparation Products

THIAZOLE-2-CARBOXYLIC ACID 2-Bromo-5-fomylthiazole 1,3-Thiazole-2-carbonyl chloride Thiazole-5-carboxylic acid 5-Bromothiazole
camalexin 2-Thiazolesulfonyl chloride 4-Thiazoline-2-one 2-(METHYLTHIO)THIAZOLE 2-Cyanothiazole
1-(1,3-thiazol-2-yl)-1,4-diazepane 3-(1,3-THIAZOL-2-YL)BENZALDEHYDE pyridin-2-yl(thiazol-2-yl)Methanone 2-Trifluoromethyl-thiazole

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2-Bromothiazole Suppliers

Global( 466)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81138252 +86-18789408387 1057@dideu.com China 3958 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20286 58
JINING XINHE CHEMICAL CO., LTD 		+8615318402391 sales@xinhepharma.com China 809 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
Biochempartner 		0086-13720134139 candy@biochempartner.com CHINA 965 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8618959220845 sales@amoychem.com China 6383 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
Supplier Advantage
Shaanxi Dideu Medichem Co. Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
JINING XINHE CHEMICAL CO., LTD 		58
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Biochempartner 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Xiamen AmoyChem Co., Ltd 		58
Chongqing Chemdad Co., Ltd 		58
Wuhan Chemwish Technology Co., Ltd 		58

View Lastest Price from 2-Bromothiazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromothiazole pictures 2024-07-22 2-Bromothiazole
3034-53-5
 US $0.00-0.00 / kg 1kg 98% 10ton JINING XINHE CHEMICAL CO., LTD
2-Bromothiazole pictures 2024-07-18 2-Bromothiazole
3034-53-5
 US $1.00 / Kg 1Kg 98% 20T Shaanxi Dideu Medichem Co. Ltd
2-Bromothiazole pictures 2024-04-22 2-Bromothiazole
3034-53-5
 US $32.00-1.10 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
  • 2-Bromothiazole pictures
  • 2-Bromothiazole
    3034-53-5
  • US $0.00-0.00 / kg
  • 98%
  • JINING XINHE CHEMICAL CO., LTD
  • 2-Bromothiazole pictures
  • 2-Bromothiazole
    3034-53-5
  • US $32.00-1.10 / kg
  • 99%
  • Henan Fengda Chemical Co., Ltd

2-Bromothiazole Spectrum

2-Bromothiazole(3034-53-5)MS2-Bromothiazole(3034-53-5)1HNMR2-Bromothiazole(3034-53-5)13CNMR2-Bromothiazole(3034-53-5)IR1

3034-53-5(2-Bromothiazole)Related Search:

2,2'-Dithiobis(benzothiazole) Thiazole Benzothiazole 2-Mercaptobenzothiazole Fosthiazate
3-Bromoanisole Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) 2-(2-Aminothiazol-4-yl)glyoxylic acid 2-BROMOCARBAZOLE 2-Bromonaphthalene
2-Bromo-1,3-benzothiazole 2,4-BROMOTHIAZOLE 2-BROMO-4-CHLOROBENZOTHIAZOLE 2-BROMOTHIAZOLE-5-METHANOL ETHYL 2-BROMO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE
2-BROMOTHIAZOLE-4-METHANOL 2-BROMOTHIAZOLE-4-CARBALDEHYDE 2-BROMOTHIAZOLE-5-CARBOXYLIC ACID

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2-THIAZOLYL BROMIDE 2-BROMOTHIOAZOLE 2-BROMOTHIAZOLE TIMTEC-BB SBB003918 2-Bromothiazole, 98+% Thiazole, 2-bromo- 2-bromo-thiazol 2-BROMOTHIAZOLE 99+% 2-BroMothiazole, 98+% 25ML 2-BroMothiazole, 98+% 5ML NSC 91532 2-BROMOTHIAZOLE FOR SYNTHESIS 2 - broMine thiazole CL028 TZ-Br N,N'-bis(2,4-dinitrophenyl)ethane-1,2-diamine 2-Bromthiazol 2-Bromothiazole > 2-bromothiazole-4,5-d2 2-BROMO-1,3-THIAZOLE 3034-53-5 3430-53-5 C3H2BrNS C3H2SNBr -SCHCHNCBr Thiazoles Halogenated Heterocycles Heterocyclic Building Blocks Building Blocks alkyl bromide Building Blocks C3 to C7 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Sulfur & Selenium Compounds Thiazoles, Isothiazoles & Benzothiazoles Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Heterocyclic Compounds Thiazoles Halides Heterocycles ThiazolesHeterocyclic Building Blocks Thiazoles, Isothiazoles &Benzothiazoles API intermediates Organohalides Thiazole API