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Mal-PEG2-oxyamine

CAS No.
1146245-73-9
Chemical Name:
Mal-PEG2-oxyamine
Synonyms
Mal-PEG2-oxyamine;1H-Pyrrole-2,5-dione, 1-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethyl]-
CBNumber:
CB18054747
Molecular Formula:
C10H16N2O5
Molecular Weight:
244.24
MDL Number:
MFCD31715339
MOL File:
1146245-73-9.mol
Last updated:2024-07-02 08:55:01

Mal-PEG2-oxyamine Properties

Boiling point 424.3±35.0 °C(Predicted)
Density 1.269±0.06 g/cm3(Predicted)
pka 4.21±0.70(Predicted)
form Oil
color Colorless to light yellow

Mal-PEG2-oxyamine Chemical Properties,Uses,Production

Biological Activity

Mal-PEG2-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Mal-PEG2-oxyamine Preparation Products And Raw materials

Raw materials

Preparation Products

Mal-PEG2-oxyamine Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7887 56
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 Gsiyu@solarbio.com China 50471 58
Suzhou Meidi Senuo Pharmaceutical Technology Co., Ltd. 13771642864 snhuyu_2008@126.com China 1108 58
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 hanfangpharma@126.com China 30968 58
Mal-PEG2-oxyamine 1H-Pyrrole-2,5-dione, 1-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethyl]- 1146245-73-9