6-Chloro-4-ethynyl-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

6-Chloro-4-ethynyl-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one structure

CAS No.: 168834-32-0

Chemical Name:: 6-Chloro-4-ethynyl-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

Synonyms: 6-Chloro-4-ethynyl-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;2H-3,1-Benzoxazin-2-one, 6-chloro-4-ethynyl-1,4-dihydro-4-(trifluoromethyl)-

CBNumber:: CB18394216

Molecular Formula:: C11H5ClF3NO2

Molecular Weight:: 275.61

MDL Number:

MOL File:: 168834-32-0.mol

Request For Quotation

6-Chloro-4-ethynyl-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one Properties

Boiling point	263.8±40.0 °C(Predicted)
Density	1.56±0.1 g/cm3(Predicted)
pka	10.38±0.40(Predicted)

6-Chloro-4-ethynyl-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one Chemical Properties,Uses,Production

Uses

6-Chloro-4-ethynyl-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one is an intermediate in the synthesis of (4S)-6-Chloro-1-(1-((S)-6-chloro-2-oxo-4-(trifluoromethyl)-2,4-dihydro-1H-benzo[d][1,3]oxazin-4-yl)pent-1-yn-3-yl)-4-(pent-1-yn-1-yl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one (C360050), an impurity of Efavirenz (E425000) which is a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.

6-Chloro-4-ethynyl-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

6-Chloro-4-ethynyl-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one 2H-3,1-Benzoxazin-2-one, 6-chloro-4-ethynyl-1,4-dihydro-4-(trifluoromethyl)- 168834-32-0