caramiphen hydrogen edisilate

CAS No.
125-86-0
Chemical Name:
caramiphen hydrogen edisilate
Synonyms
Ethanedisulfonate;BANIDACEBXZGNK-UHFFFAOYSA-N;Caramiphen ethanedisulfonate;caramiphen hydrogen edisilate;2-diethylaminoethyl 2-phenylcyclopentane-1-carboxylate;2-phenylcyclopentanecarboxylic acid 2-diethylaminoethyl ester;Bis[1-(carbo-β-diethylaminoethoxy)-1-phenylcyclopentane]ethanedisulfonate
CBNumber:
CB1877872
Molecular Formula:
2C18H27NO2.C2H6O6S2
Molecular Weight:
769.028
MDL Number:
MFCD00242609
MOL File:
125-86-0.mol
Last updated:2023-05-04 15:15:43

caramiphen hydrogen edisilate Properties

Melting point 115-116°
FDA UNII 09TQU5PG95

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501

caramiphen hydrogen edisilate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B416465 Bis[1-(carbo-β-diethylaminoethoxy)-1-phenylcyclopentane]ethanedisulfonate 125-86-0 500mg $90 2021-12-16 Buy
Product number Packaging Price Buy
B416465 500mg $90 Buy

caramiphen hydrogen edisilate Chemical Properties,Uses,Production

Originator

Panparnit,Geigy,US,1949

Uses

Bis[1-(carbo-β-diethylaminoethoxy)-1-phenylcyclopentane]ethanedisulfonate is an anticholinergic and antiglutamatergic drug, which has also found use as an antidote against oragnophosphate poisoning.

Manufacturing Process

20.8 parts of 1-phenylcyclopentyl-1-carboxylic acid chloride, obtained from the acid (cf. Am. Soc. 1934, 56, 715) by means of thionyl chloride, are dissolved in 250 parts by volume of absolute ether, then, while stirring and cooling with a mixture of common salt and ice a solution of 12 parts of diethylaminoethanol in 50 parts by volume of absolute ether is allowed to drop there into, the temperature being maintained below 0°C, whereupon stirring is continued during 2 hours at room temperature. The whole is then twice shaken out with water and once with diluted hydrochloric acid, the combined aqueous solutions are made alkaline with a potassium carbonate solution and shaken out with ether. The ethereal solution is washed with water, dried over potassium carbonate and the solvent is distilled off. The base boils at a pressure of 0.07 mm at 112°C to 115°C.
The base may then be converted to the hydrochloride or to the ethanedisulfonic acid salt (edisylate).

Therapeutic Function

Antitussive

caramiphen hydrogen edisilate Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd 029-61856358 15229202216 1020@dideu.com China 10011 58
Supplier Advantage
Shaanxi Dideu Medichem Co. Ltd 58
caramiphen hydrogen edisilate Caramiphen ethanedisulfonate 2-diethylaminoethyl 2-phenylcyclopentane-1-carboxylate 2-phenylcyclopentanecarboxylic acid 2-diethylaminoethyl ester Ethanedisulfonate BANIDACEBXZGNK-UHFFFAOYSA-N Bis[1-(carbo-β-diethylaminoethoxy)-1-phenylcyclopentane]ethanedisulfonate 125-86-0