lithium hydrogenacetylide
- CAS No.
- 1111-64-4
- Chemical Name:
- lithium hydrogenacetylide
- Synonyms
- Lithioethyne;Ethynyllithium;Ethinyl lithiuM;Lithioacetylene;LITHIUM ACETYLENIDE;Monolithium acetylide;lithium hydrogenacetylide
- CBNumber:
- CB1888948
- Molecular Formula:
- C2HLi
- Molecular Weight:
- 31.97
- MDL Number:
- MOL File:
- 1111-64-4.mol
lithium hydrogenacetylide Chemical Properties,Uses,Production
Definition
ChEBI: An alkynyllithium compound resulting from the replacement of one of the hydrogens of acetylene by lithium.
Application
Lithium Acetylide is a reagent for adding Acetylene to ketones, opening epoxides, and ethynylation of alkyl halides.
Synthesis
Monolithium lithium acetylide is prepared by treating a THF solution of Acetylene with n-Butyllithium at 78 °C (eq 1). It is critical to keep the temperature at -78 °C. The concentration should be 0.5 M or less. At higher concentrations and temperatures, a white precipitate forms (presumably Dilithium Acetylide), and yields of additional product fall appreciably. Properly formed lithium acetylide in THF should be a clear, colorless solution.
Precautions
Lithium acetylide/THF solution must be used immediately after preparation. It decomposes above -78 °C. A saturated solution of THF/acetylene should not be used during the preparation of lithium acetylide since this may lead to an acetylene atmosphere above the THF. n-Butyllithium dropping through the acetylene atmosphere may react violently. Lithium acetylide is air and moisture sensitive.
lithium hydrogenacetylide Preparation Products And Raw materials
Raw materials
Preparation Products
lithium hydrogenacetylide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | 029-029-81124267 15229202216 | 1073@dideu.com | China | 9971 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 18112977050 | cb5@aikonchem.com | China | 10526 | 58 |
| Huangshi Bo’Er Chemical Co., Ltd. | 0714-6401888 18671400300 | 273568016@qq.com | China | 548 | 58 |
| Supplier | Advantage |
|---|---|
| Shaanxi Dideu Medichem Co. Ltd | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 58 |
| Huangshi Bo’Er Chemical Co., Ltd. | 58 |