Vobtusine

Description

An alkaloid of Voacanga species, this base occurs chiefly in V. african a, v. dregii and V. obtusa. It yields clusters of colourless crystals from MeOH-CHCI3 and has [(dD - 321° (c 1.0, CHCI3). It is insoluble in most organic solvents but dissolves in CHCI3. The hydrochloride has m.p. 242-4°C; the hydro bromide, m.p. 290°C (dec.) and the picrate, m.p. 206-2100 C, decomposing at 300°C.

Definition

ChEBI: Vobtusine is an indole alkaloid fundamental parent, an alkaloid ester, a vinca alkaloid, a hemiaminal, a methyl ester and a spiro compound.

References

Janot, Goutarel., Compt. rend., 240, 1719 (1955) Schuller, Verbeck, Warren.,]. Chem. Soc., 4776 (1958) Stauffacher, Seebeck., Helv. Chim. Acta, 41,169 (1958) Goutarel et al., Bull. Soc. Chim. Fr., 893 (1959)

Raw materials

Preparation Products