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ChemicalBook >> CAS DataBase List >>Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester

Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester

Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester Structure
Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester structure
CAS No.
1620160-42-0
Chemical Name:
Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester
Synonyms
Honokiol DCA;Honokiol Bis-Dichloroacetate;Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester
CBNumber:
CB19270278
Molecular Formula:
C22H18Cl4O4
Molecular Weight:
488.19
MDL Number:
MFCD34469330
MOL File:
1620160-42-0.mol
Last updated:2024-10-28 16:48:35
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Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester Properties

Boiling point 537.9±50.0 °C(Predicted)
Density 1.337±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
form Liquid
color Colorless to light yellow

Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester Chemical Properties,Uses,Production

Biological Activity

Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level[1]. Honokiol DCA (20-40 μM; 24-48 h) inhibits the viability of LNCaP and C4-2 cells in a dose-and time-dependent manner[1].Honokiol DCA (5-20 μM; 10 days) inhibits clonogenicity of prostate cancer cells[1].Honokiol DCA (20-40 μM; 24-48 h) significantly decreases the level of androgen receptor (AR) and prostate specific antigen (PSA) protein in LNCaP cells[1].Honokiol DCA (40 μM; 24 h) significantly decreases AR promoter activity in LNCaP and C4-2 cells[1]. Honokiol类似物

References

[1]. Hahm ER, et, al. Honokiol inhibits androgen receptor activity in prostate cancer cells. Prostate. 2014 Apr;74(4):408-20.

Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19884 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19703 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
TargetMol Chemicals Inc. 		58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

View Lastest Price from Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Honokiol DCA pictures 2024-10-28 Honokiol DCA
1620160-42-0
 US $95.00-789.00 / mg 10g TargetMol Chemicals Inc.
  • Honokiol DCA pictures
  • Honokiol DCA
    1620160-42-0
  • US $95.00-789.00 / mg
  • TargetMol Chemicals Inc.
Acetic acid, 2,2-dichloro-, 2'-[(2,2-dichloroacetyl)oxy]-3,5'-di-2-propen-1-yl[1,1'-biphenyl]-4-yl ester Honokiol Bis-Dichloroacetate Honokiol DCA 1620160-42-0 C22H18Cl4O4