ChemicalBook >> CAS DataBase List >>1-Piperazineethanol, 4-(2-phenyl-4-quinazolinyl)-
1-Piperazineethanol, 4-(2-phenyl-4-quinazolinyl)-
- CAS No.
- 345651-04-9
- Chemical Name:
- 1-Piperazineethanol, 4-(2-phenyl-4-quinazolinyl)-
- Synonyms
- BVDV IN-1;1-Piperazineethanol, 4-(2-phenyl-4-quinazolinyl)-;2-(4-(2-Phenylquinazolin-4-yl)piperazin-1-yl)ethanol;inhibit,virus,non-nucleoside,BVDV IN 1,activity,bovine,viral,antiviral,inhibitor,BVDVIN1,DNA/RNA Synthesis,diarrhea
- CBNumber:
- CB19310567
- Molecular Formula:
- C20H22N4O
- Molecular Weight:
- 334.41
- MDL Number:
- MFCD10154938
- MOL File:
- 345651-04-9.mol
Last updated:2024-07-02 08:55:01
1-Piperazineethanol, 4-(2-phenyl-4-quinazolinyl)- Chemical Properties,Uses,Production
Biological Activity
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. BVDV-IN-1 directly binds to a hydrophobic pocket of the BVDV RdRp. BVDV-IN-1 has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC)[1]. BVDV-IN-1 (compound 1.9) binds to a hydrophobic pocket of the BVDV RNA-dependent RNA polymerase (RdRp)[1].BVDV-IN-1 inhibits the replication of TSC-resistant BVDV variants in vitro[1].
References
[1]. Gabriela A Fernández, et al. Design and Optimization of Quinazoline Derivatives: New Non-nucleoside Inhibitors of Bovine Viral Diarrhea Virus. Front Chem. 2020 Dec 10;8:590235.
1-Piperazineethanol, 4-(2-phenyl-4-quinazolinyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
1-Piperazineethanol, 4-(2-phenyl-4-quinazolinyl)- Suppliers
Global( 8)Suppliers
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TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
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1-Piperazineethanol, 4-(2-phenyl-4-quinazolinyl)-
BVDV IN-1
inhibit,virus,non-nucleoside,BVDV IN 1,activity,bovine,viral,antiviral,inhibitor,BVDVIN1,DNA/RNA Synthesis,diarrhea
2-(4-(2-Phenylquinazolin-4-yl)piperazin-1-yl)ethanol
345651-04-9