Bendamustine
- CAS No.
- 97832-05-8
- Chemical Name:
- Bendamustine
- Synonyms
- Bendamustine;Bendamustine USP/EP/BP;Phenol,5-iodo-7-methyl-;4-[5-[Bis(2-chloroethyl)amino]-1-methyl-benzimidazol-2-yl]butyric acid hydrochloride
- CBNumber:
- CB1947357
- Molecular Formula:
- C16H21Cl2N3O2.HCl
- Molecular Weight:
- 394.72
- MDL Number:
- MFCD00866481
- MOL File:
- 97832-05-8.mol
- MSDS File:
- SDS
FDA UNII | 9266D9P3PQ |
---|---|
ATC code | L01AA09 |
Bendamustine price
Bendamustine Chemical Properties,Uses,Production
Uses
Bendamustine is an intermediate in the synthesis of Bendamustine 3-Hydroxyprop-2-yl Ester (B132550), which is an impurity of anticancer drug Bendamustine Hydrochloride (B132500).
Enzyme inhibitor
This nitrogen mustard and anticancer drug (FWfree-acid = 358.26 g/mol; CAS 16506-27-7), also known by its code name SDX-105, its trade names Treanda?, Treakisym?, Ribomustin?, and Levact?, as well as by its systematic name 4-[5-[bis (2-chloroethyl) amino]-1-methylbenzimidazol-2- yl]butanoic acid, is a relatively nonspecific DNA alkylating agent that causes intra- and inter-strand cross-links. Bendamustine is used in the treatment of chronic lymphocytic leukemia (CLL), Hodgkin’s disease, non- Hodgkin’s lymphoma, multiple myeloma and lung cancer. Pharmacokinetics: After intravenous infusion, >95% of the drug becomes protein-bound, mainly to albumin; however, only free bendamustine is active. Bendamustine is metabolized by liver cytochrome p450, and elimination (renal) is biphasic, with an initial half-life of 6–10 minutes and a terminal half-life of approximately 30 minutes.
Bendamustine Preparation Products And Raw materials
Raw materials
Preparation Products
Bendamustine Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 24330 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15395 | 58 |
sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046 | sales01@watsonbiotech.cn | China | 5853 | 58 |
View Lastest Price from Bendamustine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-06 | Bendamustine USP/EP/BP
97832-05-8
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | ||
2020-11-16 | Bendamustine
97832-05-8
|
US $20.00 / KG | 1KG | 99% | 1000kg | Longyan Tianhua Biological Technology Co., Ltd | ||
2019-09-02 | Bendamustine
97832-05-8
|
US $1.00-2.00 / KG | 1KG | 98% | 200kg | Career Henan Chemical Co |
- Bendamustine USP/EP/BP
97832-05-8
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
- Bendamustine
97832-05-8
- US $20.00 / KG
- 99%
- Longyan Tianhua Biological Technology Co., Ltd
- Bendamustine
97832-05-8
- US $1.00-2.00 / KG
- 98%
- Career Henan Chemical Co