Benzoic acid, 4-[4-[(2R,5R)-5-[[bis(phenylmethyl)amino]carbonyl]-2-heptyl-4-oxo-3-thiazolidinyl]butyl]-, rel-
![Benzoic acid, 4-[4-[(2R,5R)-5-[[bis(phenylmethyl)amino]carbonyl]-2-heptyl-4-oxo-3-thiazolidinyl]butyl]-, rel- Structure](CAS/20210305/GIF/321557-86-2.gif)
- CAS No.
- 321557-86-2
- Chemical Name:
- Benzoic acid, 4-[4-[(2R,5R)-5-[[bis(phenylmethyl)amino]carbonyl]-2-heptyl-4-oxo-3-thiazolidinyl]butyl]-, rel-
- Synonyms
- GW0072;GW-0072;GW 0072;Benzoic acid, 4-[4-[(2R,5R)-5-[[bis(phenylmethyl)amino]carbonyl]-2-heptyl-4-oxo-3-thiazolidinyl]butyl]-, rel-
- CBNumber:
- CB19819848
- Molecular Formula:
- C36H44N2O4S
- Molecular Weight:
- 600.81
- MDL Number:
- MOL File:
- 321557-86-2.mol
Benzoic acid, 4-[4-[(2R,5R)-5-[[bis(phenylmethyl)amino]carbonyl]-2-heptyl-4-oxo-3-thiazolidinyl]butyl]-, rel- Properties
| Boiling point | 811.2±65.0 °C(Predicted) |
|---|---|
| Density | 1.164±0.06 g/cm3(Predicted) |
| pka | 4.34±0.10(Predicted) |
| FDA UNII | 31O7M7ZCCF |
Benzoic acid, 4-[4-[(2R,5R)-5-[[bis(phenylmethyl)amino]carbonyl]-2-heptyl-4-oxo-3-thiazolidinyl]butyl]-, rel- Chemical Properties,Uses,Production
Uses
GW0072 is a partial agonist of PPARγ and does not directly bind to the AF-2 helix of PPARγ, resulting in specific partial receptor transcriptional activation properties[1][2].
References
[1] Ligand entry pathways in the ligand binding domain of PPARc receptor
[2] Genest D, et al. Ligand-escape pathways from the ligand-binding domain of PPARgamma receptor as probed by molecular dynamics simulations. Eur Biophys J. 2008 Apr;37(4):369-79. DOI:10.1007/s00249-007-0220-9
[3] Zhang F, et al. Selective Modulators of PPAR-gamma Activity: Molecular Aspects Related to Obesity and Side-Effects. PPAR Res. 2007;2007:32696. DOI:10.1155/2007/32696
Benzoic acid, 4-[4-[(2R,5R)-5-[[bis(phenylmethyl)amino]carbonyl]-2-heptyl-4-oxo-3-thiazolidinyl]butyl]-, rel- Preparation Products And Raw materials
Raw materials
Preparation Products
Benzoic acid, 4-[4-[(2R,5R)-5-[[bis(phenylmethyl)amino]carbonyl]-2-heptyl-4-oxo-3-thiazolidinyl]butyl]-, rel- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32222 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19893 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19784 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
