ChemicalBook >> CAS DataBase List >>GS-441524 HCl
GS-441524 HCl
- CAS No.
- 2378280-82-9
- Chemical Name:
- GS-441524 HCl
- Synonyms
- GS-441524 HCl
- CBNumber:
- CB210234398
- Molecular Formula:
- C12H14ClN5O4
- Molecular Weight:
- 327.73
- MDL Number:
- MOL File:
- 2378280-82-9.mol
Last updated:2023-03-31 09:12:59
GS-441524 HCl Chemical Properties,Uses,Production
Description
GS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an EC50 of 0.78 μM.. GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. GS-441524 is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase. GS-441524 was non-toxic in feline cells at concentrations as high as 100?uM and effectively inhibited FIPV replication in cultured CRFK cells and in naturally infected feline peritoneal macrophages at concentrations as low as 1 uM. Note: GS-441524 is an active metabolite of Remdesivir.
target
TBD
GS-441524 HCl Preparation Products And Raw materials
Raw materials
Preparation Products
GS-441524 HCl Suppliers
Global( 3)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| InvivoChem | 13549236410 | sales@invivochem.cn | China | 6755 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19696 | 58 |
| Supplier | Advantage |
|---|---|
| InvivoChem | 58 |
| InvivoChem | 58 |
| TargetMol Chemicals Inc. | 58 |
GS-441524 HCl
2378280-82-9