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ChemicalBook >> CAS DataBase List >>1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-

1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-

1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]- Structure
1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]- structure
CAS No.
2446817-72-5
Chemical Name:
1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-
Synonyms
APOL1-IN-1;1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-
CBNumber:
CB210475072
Molecular Formula:
C21H20FN3O3
Molecular Weight:
381.4
MDL Number:
MOL File:
2446817-72-5.mol
Last updated:2024-11-06 15:28:16
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1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]- Properties

Boiling point 801.4±65.0 °C(Predicted)
Density 1.40±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 125 mg/mL (327.74 mM; Need ultrasonic)
pka 13.03±0.40(Predicted)
form Solid
color White to off-white

1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]- Chemical Properties,Uses,Production

Biological Activity

APOL1-IN-1 is a apolipoprotein L1 (APOL1) inhibitor extracted from patent WO2020131807A1 compound 87. APOL1-IN-1 can be used for the research of focal segmental glomerulosclerosis (FSGS) and non-diabetic kidney disease (NDKD)[1].

References

[1]. Brodney M, et, al. Inhibitors of apol1 and methods of using same. WO2020131807A1.

1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]- Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32072 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3466 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9410 58
Chunchuang (Wuhan) Technology Co., Ltd 15342225168 yutianchun2007@126.com China 10002 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24648 58
Suzhou Haiben Pharmaceutical Co., Ltd 14760821013 13564957716 1816280386@qq.com China 7327 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
DC Chemicals 58
Chunchuang (Wuhan) Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
Suzhou Haiben Pharmaceutical Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58

View Lastest Price from 1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
APOL1-IN-1 pictures 2024-11-06 APOL1-IN-1
2446817-72-5
 US $117.00-496.00 / mg 99.76% 10g TargetMol Chemicals Inc.
  • APOL1-IN-1 pictures
  • APOL1-IN-1
    2446817-72-5
  • US $117.00-496.00 / mg
  • 99.76%
  • TargetMol Chemicals Inc.
1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]- APOL1-IN-1 2446817-72-5