Hexylcainc
- CAS No.
- 532-77-4
- Chemical Name:
- Hexylcainc
- Synonyms
- Hexylcainc;1-(Cyclohexylamino)-2-propanol benzoate;1-(cyclohexylamino)propan-2-yl benzoate;2-Propanol, 1-(cyclohexylamino)-, 2-benzoate;Benzoic acid 2-cyclohexylamino-1-methylethyl ester;Benzoic acid 1-(cyclohexylamino)-2-methylethyl ester
- CBNumber:
- CB21178898
- Molecular Formula:
- C16H23NO2
- Molecular Weight:
- 261.36
- MDL Number:
- MFCD00864417
- MOL File:
- 532-77-4.mol
Boiling point | 385.3±25.0 °C(Predicted) |
---|---|
Density | 1.05±0.1 g/cm3(Predicted) |
solubility | soluble in Dichloromethane |
form | Solid |
pka | 9.02±0.20(Predicted) |
color | White |
FDA UNII | 511IU0826Z |
Hexylcainc Chemical Properties,Uses,Production
Originator
Cyclaine,MSD,US,1952
Uses
Hexylcaine is an intermediate in the synthesis of Hexylcaine Hydrochloride which is used in pain management in as an antifungal agent. Anaesthetic.
Definition
ChEBI: Hexylcaine is a benzoate ester.
Manufacturing Process
A solution of 0.1 mol of 1-cyclohexylamino-2-propanol in 30 grams of
chloroform was saturated with dry hydrogen chloride gas, with cooling. A
solution of 0.1 mol of benzoyl chloride in 30 grams of chloroform was added
and the solution was heated in a bath at 50° to 55°C for four days under a
reflux condenser protected from atmospheric moisture. Then the solvent was
removed by vacuum distillation while the mixture was warmed on a water
bath. Benzene was then added to the syrupy residue and the reaction product
crystallized out after the benzene was removed by vacuum distillation.
The crystallized solid residue was washed with anhydrous ether to remove any
unreacted benzoyl chloride. The 1-cyclohexylamino-2-propyl benzoate
hydrochloride obtained was purified by two recrystallizations from absolute
alcohol. It melted at 177° to 178.5°C.
Therapeutic Function
Local anesthetic
Safety Profile
Human systemic effects. When heated to decomposition it emits toxic vapors of NOx.
Hexylcainc Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 8722 | 58 |
Supplier | Advantage |
---|---|
Hubei Jusheng Technology Co.,Ltd. | 58 |
Shaanxi Didu New Materials Co. Ltd | 58 |