Cyromazine
- CAS No.
- 66215-27-8
- Chemical Name:
- Cyromazine
- Synonyms
- CIROMAZIN;CYROMAZIN;N2-CYCLOPROPYL-1,3,5-TRIAZINE-2,4,6-TRIAMINE;ARMOR;neoprex;TRIGARD;NEPOREX;Neoprox;cga72662;ARMOR(R)
- CBNumber:
- CB2120418
- Molecular Formula:
- C6H10N6
- Molecular Weight:
- 166.18
- MDL Number:
- MFCD00078650
- MOL File:
- 66215-27-8.mol
- MSDS File:
- SDS
| Melting point | 223-227 °C (lit.) |
|---|---|
| Boiling point | 284.39°C (rough estimate) |
| Density | 1.3196 (rough estimate) |
| vapor pressure | 4.5 x l0-7 Pa (25 °C) |
| refractive index | 1.8300 (estimate) |
| Flash point | 100 °C |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 5.2 (base) |
| Water Solubility | 13 g l-1 (pH 7.1,25 °C) |
| color | White to Off-White |
| Merck | 14,2775 |
| BRN | 882879 |
| Stability | Hygroscopic |
| InChIKey | LVQDKIWDGQRHTE-UHFFFAOYSA-N |
| LogP | -0.061 at 25℃ |
| CAS DataBase Reference | 66215-27-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | CA49Y29RA9 |
| NIST Chemistry Reference | Cyromazine(66215-27-8) |
| EPA Substance Registry System | Cyromazine (66215-27-8) |
| Pesticides Freedom of Information Act (FOIA) | Cyromazine |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H411 | |||||||||
| Precautionary statements | P273-P391-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN3077 (solid) | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | XZ1056500 | |||||||||
| HS Code | 29336990 | |||||||||
| Hazardous Substances Data | 66215-27-8(Hazardous Substances Data) | |||||||||
| Toxicity | LC50 (96-hour) for rainbow trout and carp >100 mg/L and bluegill sunfish >90 mg/L (Hartley and Kidd, 1987); acute oral LD50 for rats 3,387 mg/kg (Hartley and Kidd, 1987) | |||||||||
| NFPA 704 |
|
Cyromazine price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2899 | Cyromazine pharmaceutical secondary standard, certified reference material | 66215-27-8 | 500MG | $172 | 2024-03-01 | Buy |
| Sigma-Aldrich | 45414 | Cyromazin PESTANAL , analytical standard | 66215-27-8 | 50mg | $90.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1161203 | Cyromazin United States Pharmacopeia (USP) Reference Standard | 66215-27-8 | 200mg | $457 | 2024-03-01 | Buy |
| TCI Chemical | C2366 | Cyromazine >98.0%(HPLC)(T) | 66215-27-8 | 5g | $36 | 2024-03-01 | Buy |
| TCI Chemical | C2366 | Cyromazine >98.0%(HPLC)(T) | 66215-27-8 | 25g | $39 | 2024-03-01 | Buy |
Cyromazine Chemical Properties,Uses,Production
Description
Cyromazine is a triazine insect growth regulator that can be used as an insecticide and an acarcide. It is a kind of cyclopropylderivative of melamine, and also belongs to the family of aminotriazines which are compound consisting of an amino group attached to a triazine ring. It has specific activity against dipterous larvae, and has been approved by FDA for being applied to livestock. It is not a kind of cholinesterase inhibitor, and taking effect through affecting the nervous system of the immature larval stage of the insects.
References
https://pubchem.ncbi.nlm.nih.gov/compound/cyromazine#section=Top
https://en.wikipedia.org/wiki/Cyromazine
http://pmep.cce.cornell.edu/profiles/insect-mite/cadusafos-cyromazine/cyromazine/insect-prof-cyromazine.html
Chemical Properties
White crystalline powder. The solubility in water is 11,000 mg/L at 20°C and pH 7.5, and the hydrolysis is not obvious at pH 5-9.
Uses
Cypromazine is a high-efficiency and low-toxicity insecticide. It is mainly used to control leafminer pests, has a good control effect on Liriomyza, and can also be used to control flies.
Application
Cyromazine is an insect growth regulator, used to control fly larvae in livestock and poultry manure. It can be fed directly to livestock or applied directly to fly breeding sites. Cyromazine also exhibits systemic activity and is used as a foliar spray to control leaf miners in vegetables, potatoes, etc., and on mushrooms.
Preparation
Cyromazine is prepared by the reaction of cyanuric chloride and cyclopropylamine to obtain 2-Cyclopropylamino-4,6-dichloro-triazepine, and then reacts with ammonia to obtain 2-Cyclopropylamino-4-chloro-6-aminostriazepine, and then reacting with ammonia to produce.
Definition
ChEBI: Cyromazine is a triamino-1,3,5-triazine. It has a role as a triazine insecticide and a mouse metabolite.
General Description
N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine, also known as cyromazine, is an insect growth regulator(IGR) that is commonly used as an insecticide. It undergoes metabolism in plants and animals to form melamine. Surface-enhanced Raman scattering (SERS) spectroscopic study indicates that it interacts with the surface of silver colloid through the lone pair on nitrogen.
Flammability and Explosibility
Not classified
Agricultural Uses
Insecticide (insect growth regulator): As an insect growth regulator, cyromazine is fed to caged poultry and is passed through the chicken, leaving a residue in the manure. The chemical controls the growth of the fly larvae developing in the manure. Used as a foliar spray to control leaf miners in vegetables, mushrooms, potatoes and ornamentals and to control flies on animals.
Trade name
ARMOR®; CITATION; CGA-72662®; LARVADEX®; PATRON®; TRIGARD®; VETRAZIN®
Environmental Fate
Chemical/Physical. Cyromazine will react with mineral acids (e.g., hydrochloric acid, sulfuric acid) forming water-soluble salts
Metabolic pathway
Information presented in this summary is abstracted from the data evaluation published by the Pesticide Safety Directorate (PSD, 1993). The major degradation pathway of cyromazine involves the N-dealkylation of the cyclopropyl moiety to yield melamine. Both cyromazine and melamine are quite stable to biotransformation. Deamination and the formation of N-methylcyromazine were observed as minor pathways.
Degradation
Cyromazine (1) is stable to hydrolysis at pH 5, 7 and 9 and 70 °C for up to 28 days. No degradation of cyromazine was observed when irradiated under mercury vapour lamp (>290 nm) at 25 °C for up to 168 hours.
Cyromazine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Suikang Pharmaceutical Co.,Ltd. | +86-18239973690 +86-18239973690 | sales@suikangpharm.com | China | 311 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8806 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3882 | 58 |
| Qingdao Trust Agri Chemical Co.,Ltd | +8613573296305 | aroma@qdtrustagri.com | China | 301 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659 +86-13153181156 | sales@sdperfect.com | China | 294 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20282 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
| Hebei Mojin Biotechnology Co.,Ltd | +86-15028179902 | angelia@hbmojin.com | China | 1176 | 58 |
Related articles
- Cyromazine: Applications as Insecticides and its Biodegradation
- Cyromazine targets insect reproduction via ecdysone signaling and is biodegraded by specific bacteria, offering dual benefits ....
- Jun 20，2024
View Lastest Price from Cyromazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-01-03 | Cyromazine
66215-27-8
|
US $0.00 / kg | 25kg | ≥98.0% | 10tons | Henan Suikang Pharmaceutical Co.,Ltd. | |
 |
2025-01-03 | Cyromazine
66215-27-8
|
US $120.00 / kg | 1kg | 99% | 10ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-12-27 | Cyromazine
66215-27-8
|
US $0.00-0.00 / Kg/Drum | 1KG | 98%-102%; USP | 1000 KG | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- Cyromazine
66215-27-8
- US $0.00 / kg
- ≥98.0%
- Henan Suikang Pharmaceutical Co.,Ltd.
-
- Cyromazine
66215-27-8
- US $120.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Cyromazine
66215-27-8
- US $0.00-0.00 / Kg/Drum
- 98%-102%; USP
- WUHAN FORTUNA CHEMICAL CO., LTD