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INDEX NAME NOT YET ASSIGNED

INDEX NAME NOT YET ASSIGNED structure

CAS No.: 2758431-97-7

Chemical Name:: INDEX NAME NOT YET ASSIGNED

Synonyms: MD13;MIF degrader MD13

CBNumber:: CB212153202

Molecular Formula:: C35H35N5O8

Molecular Weight:: 653.68

MDL Number:

MOL File:: Mol file

Last updated:2023-07-14 17:32:22

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INDEX NAME NOT YET ASSIGNED Properties

Boiling point	964.5±65.0 °C(Predicted)
Density	1.434±0.06 g/cm3(Predicted)
solubility	DMSO:65.37(Max Conc. mg/mL);100.0(Max Conc. mM)
pka	8.85±0.20(Predicted)

INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production

Description

MD13, also known as MIF degrader MD13, is a potent MIF (macrophage migration inhibitory factor) Degrader (PROTAC?) (DC50 < 100 nM; Dmax = 92% after 6 h). MD13 comprises the cereblon ligand Pomalidomide joined by a linker to a MIF inhibitor. MD13 reduces MIF levels, arrests cells at the G2/M phase and inhibits proliferation of A549 lung carcinoma cells. Growth of A549 cell 3D spheroids is also inhibited by MDF13.

storage

Store at -20°C

INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials

Raw materials

Preparation Products

INDEX NAME NOT YET ASSIGNED Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19696	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

MD13 MIF degrader MD13 2758431-97-7