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ChemicalBook >> CAS DataBase List >>methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate Structure
methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate structure
CAS No.
4072-32-6
Chemical Name:
methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate
Synonyms
γ-CEHC;α-CEHC;alpha-CEHC;AXODOWFEFKOVSH-UHFFFAOYSA-N;2,5,7,8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman;methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate;2H-1-Benzopyran-2-propanoic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-
CBNumber:
CB21235687
Molecular Formula:
C16H22O4
Molecular Weight:
278.34
MDL Number:
MFCD12912239
MOL File:
4072-32-6.mol
Last updated:2025-04-17 18:22:24
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methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate Properties

storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:1): .25 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10007705 α-CEHC ≥98% 4072-32-6 1mg $28 2024-03-01 Buy
Cayman Chemical 10007705 α-CEHC ≥98% 4072-32-6 5mg $117 2024-03-01 Buy
Cayman Chemical 10007705 α-CEHC ≥98% 4072-32-6 10mg $207 2024-03-01 Buy
Cayman Chemical 10007705 α-CEHC ≥98% 4072-32-6 25mg $448 2024-03-01 Buy
Product number Packaging Price Buy
10007705 1mg $28 Buy
10007705 5mg $117 Buy
10007705 10mg $207 Buy
10007705 25mg $448 Buy

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate Chemical Properties,Uses,Production

Description

Molecules having vitamin E antioxidant activity include four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ).1 α-Tocopherol is the major lipid soluble antioxidant in vivo and protects against lipid peroxidation.2 α-CEHC is the major urinary metabolite of α-tocopherol following vitamin E supplementation.3 The concentration of α-CEHC in human serum is in the range of 5-10 pmol/ml but increases significantly up to 200 pmol/ml upon supplementation with RRR-α-tocopherol. About one-third of the α-CEHC circulating in the blood is present as a glucuronide conjugate.4 α-CEHC was only excreted when a threshold concentration of 7-9 μmol α-tocopherol/g total lipid in plasma was exceeded. Therefore, excretion of α-CEHC may be considered to be a marker of optimum vitamin E intake.5

Uses

Sulfacetamide (sodium monohydrate) (Standard) is the analytical standard of Sulfacetamide (sodium monohydrate). This product is intended for research and analytical applications. 0

References

1. Kamal-Eldin, A., and Appelqvist, L.-?. The chemistry and antioxidant properties of tocopherols and tocotrienols Lipids 31(7),671-701(1996).
2. Burton, G.W., Joyce, A., and Ingold, K.U. Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes? Arch. Biochem. Biophys. 221(1),281-290(1983).
3. Traber, M.G., Elsner, A., and Brigelius-Flohé, R. Synthetic as compared with natural vitamin E is preferentially excreted as α-CEHC in human urine: Studies using deuterated α-tocopheryl acetates FEBS Lett. 437,145-148(1998).
4. Stahl, W.S., Graf, P., Brigelius-Flohé, R., et al. Quantification of the α- and γ-tocopherol metabolites 2,5,7,8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman and 2,7,8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman in human serum Anal. Biochem. 275,254-259(1999).
5. Schultz, M., Leist, M., Petrzika, M., et al. Novel urinary metabolite of α-tocopherol, 2,5,7,8-tetramethyl-2(2'-carboxyethyl)-6-hydroxychroman, as an indicator of an adequate vitamin E supply Am. J. Clin. Nutr. 62(6),1527S-1534S(1995).

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate Preparation Products And Raw materials

Raw materials

Preparation Products

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate Suppliers

Global( 13)Suppliers
Supplier Tel Email Country ProdList Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 6838 58
Hubei Rhema Reference Materials Technology Co., Ltd. 0712-8899838 15787879035 ydw9035@rmastandards.com China 8871 58
Santa Cruz Biotechnology Inc 021-60936350 scbt@scbt.com China 6594 58
Shanghai Hongyu Biotechnology Co., Ltd. 02158116080 02158116080 CHINA 0 58
Dibai Biotechnology (Nanjing) Co., Ltd. 025-58649515 025-58649515 CHINA 0 58
Shenzhen Science Biology Co., Ltd. 18617181553 18617181553 CHINA 0 58
Supplier Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Cayman Chemical Company 58
Hubei Rhema Reference Materials Technology Co., Ltd. 58
Santa Cruz Biotechnology Inc 58
Shanghai Hongyu Biotechnology Co., Ltd. 58
Dibai Biotechnology (Nanjing) Co., Ltd. 58
Shenzhen Science Biology Co., Ltd. 58
alpha-CEHC methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate 2,5,7,8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman AXODOWFEFKOVSH-UHFFFAOYSA-N 2H-1-Benzopyran-2-propanoic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl- α-CEHC γ-CEHC 4072-32-6