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ChemicalBook >> CAS DataBase List >>methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate Structure
methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate structure
CAS No.
4072-32-6
Chemical Name:
methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate
Synonyms
alpha-CEHC;γ-CEHC;α-CEHC;AXODOWFEFKOVSH-UHFFFAOYSA-N;2,5,7,8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman;methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate;2H-1-Benzopyran-2-propanoic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-
CBNumber:
CB21235687
Molecular Formula:
C16H22O4
Molecular Weight:
278.34
MDL Number:
MFCD12912239
MOL File:
4072-32-6.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24
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methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate Properties

storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:1): .25 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10007705 α-CEHC ≥98% 4072-32-6 1mg $31 2026-04-30 Buy
Cayman Chemical 10007705 α-CEHC ≥98% 4072-32-6 5mg $129 2026-04-30 Buy
Cayman Chemical 10007705 α-CEHC ≥98% 4072-32-6 10mg $228 2026-04-30 Buy
Cayman Chemical 10007705 α-CEHC ≥98% 4072-32-6 25mg $493 2026-04-30 Buy
ChemScene CS-0059472 alpha-CEHC 99.3% 4072-32-6 1mg $81 2026-06-04 Buy
Product number Packaging Price Buy
10007705 1mg $31 Buy
10007705 5mg $129 Buy
10007705 10mg $228 Buy
10007705 25mg $493 Buy
CS-0059472 1mg $81 Buy

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate Chemical Properties, Uses, Production

Description

Molecules having vitamin E antioxidant activity include four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ).1 α-Tocopherol is the major lipid soluble antioxidant in vivo and protects against lipid peroxidation.2 α-CEHC is the major urinary metabolite of α-tocopherol following vitamin E supplementation.3 The concentration of α-CEHC in human serum is in the range of 5-10 pmol/ml but increases significantly up to 200 pmol/ml upon supplementation with RRR-α-tocopherol. About one-third of the α-CEHC circulating in the blood is present as a glucuronide conjugate.4 α-CEHC was only excreted when a threshold concentration of 7-9 μmol α-tocopherol/g total lipid in plasma was exceeded. Therefore, excretion of α-CEHC may be considered to be a marker of optimum vitamin E intake.5

Uses

Sulfacetamide (sodium monohydrate) (Standard) is the analytical standard of Sulfacetamide (sodium monohydrate). This product is intended for research and analytical applications. 0

References

1. Kamal-Eldin, A., and Appelqvist, L.-. The chemistry and antioxidant properties of tocopherols and tocotrienols Lipids 31(7),671-701(1996).
2. Burton, G.W., Joyce, A., and Ingold, K.U. Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes Arch. Biochem. Biophys. 221(1),281-290(1983).
3. Traber, M.G., Elsner, A., and Brigelius-Flohé, R. Synthetic as compared with natural vitamin E is preferentially excreted as α-CEHC in human urine: Studies using deuterated α-tocopheryl acetates FEBS Lett. 437,145-148(1998).
4. Stahl, W.S., Graf, P., Brigelius-Flohé, R., et al. Quantification of the α- and γ-tocopherol metabolites 2,5,7,8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman and 2,7,8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman in human serum Anal. Biochem. 275,254-259(1999).
5. Schultz, M., Leist, M., Petrzika, M., et al. Novel urinary metabolite of α-tocopherol, 2,5,7,8-tetramethyl-2(2'-carboxyethyl)-6-hydroxychroman, as an indicator of an adequate vitamin E supply Am. J. Clin. Nutr. 62(6),1527S-1534S(1995).

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate Preparation Products And Raw materials

Raw materials

Preparation Products

methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate Suppliers

Global Suppliers ( 13)
Supplier Tel Email Country ProdList Advantage
Artis Biotech Co. Ltd. 18108108965 18108108965 sales@artisbio.com China 2550 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29873 58
Supplier Advantage
Artis Biotech Co. Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

4072-32-6 (methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate) Related Search:

D-ALPHA-TOCOTRIENOL δ-CEHC D-alpha-Tocopheryl acetate 2,7,8-Trimethyl-2-(beta-carboxy-ethyl)-6-hydroxychroman Ascorbyl glucoside
1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine

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methyl 3-(6-hydroxy-5,7,8-trimethyl-chroman-2-yl)propanoate 2,5,7,8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman AXODOWFEFKOVSH-UHFFFAOYSA-N 2H-1-Benzopyran-2-propanoic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl- α-CEHC alpha-CEHC γ-CEHC 4072-32-6