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ChemicalBook >> CAS DataBase List >>1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)-

1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)-

1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)- Structure
1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)- structure
CAS No.
2417016-23-8
Chemical Name:
1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)-
Synonyms
DNA Gyrase-IN-5;1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)-
CBNumber:
CB212598881
Molecular Formula:
C25H15BrClN5
Molecular Weight:
500.78
MDL Number:
MOL File:
2417016-23-8.mol
Last updated:2025-04-18 09:51:47
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1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)- Properties

Boiling point 754.7±60.0 °C(Predicted)
Density 1.49±0.1 g/cm3(Predicted)
pka 14.51±0.30(Predicted)

1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)- Chemical Properties,Uses,Production

Uses

DNA Gyrase-IN-5 (Compound 8I-w) is a potent DNA gyrase inhibitor with an IC50 of 0.10 μM. DNA Gyrase-IN-5 shows antibacterial activities against wild type and drug-resistant strains[1].

References

[1] Liu H, et al. Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase. Bioorg Chem. 2020 Jun;99:103807. DOI:10.1016/j.bioorg.2020.103807

1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19893 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19784 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 58

View Lastest Price from 1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DNA Gyrase-IN-5 pictures 2024-11-19 DNA Gyrase-IN-5
2417016-23-8
 US $2500.00-1520.00 / mg 10g TargetMol Chemicals Inc.
  • DNA Gyrase-IN-5 pictures
  • DNA Gyrase-IN-5
    2417016-23-8
  • US $2500.00-1520.00 / mg
  • TargetMol Chemicals Inc.
1H-Pyrazole-4-carbonitrile, 5-[(E)-[[2-(4-bromophenyl)-1H-indol-3-yl]methylene]amino]-1-(4-chlorophenyl)- DNA Gyrase-IN-5 2417016-23-8 C25H15BrClN5