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Vanillylidenacetone

CAS No.
1080-12-2
Chemical Name:
Vanillylidenacetone
Synonyms
mhsk;FEMA 3738;feruloylmethane;vanillalacetone;DEHYDROZINGERONE;Dehydrogingerone;dehydro(o)-paradol;Vanillideneacetone;VANILLYLIDENACETONE;VANILLYLIDENEACETONE
CBNumber:
CB2126546
Molecular Formula:
C11H12O3
Molecular Weight:
192.21
MDL Number:
MFCD00012210
MOL File:
1080-12-2.mol
MSDS File:
SDS
Last updated:2023-05-25 18:01:01

Vanillylidenacetone Properties

Melting point 125-130 °C
Boiling point 268.19°C (rough estimate)
Density 1.1503 (rough estimate)
refractive index 1.4600 (estimate)
FEMA 3738 | VANILLYLIDENE ACETONE
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
form solid
pka 9.94±0.31(Predicted)
color Pale yellow
Odor at 100.00 %. sweet powdery vanilla creamy balsam
Odor Type vanilla
JECFA Number 732
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
LogP 1.40
CAS DataBase Reference 1080-12-2(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) VANILLYLIDENE ACETONE
EWG's Food Scores 1
FDA UNII 8CJX5I27B7
EPA Substance Registry System 3-Buten-2-one, 4-(4-hydroxy-3-methoxyphenyl)- (1080-12-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  3
RTECS  EM9960000
10-23
HS Code  29145090
Toxicity LD50 intraperitoneal in mouse: 610mg/kg

Vanillylidenacetone price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 07551 Vanillylidenacetone ≥98.5% 1080-12-2 5G-F $102 2023-06-20 Buy
Sigma-Aldrich 07551 Vanillylidenacetone ≥98.5% 1080-12-2 5G $102 2023-01-07 Buy
Sigma-Aldrich 90609 Vanillylidenacetone analytical standard 1080-12-2 100mg $69.5 2022-05-15 Buy
TRC H533360 4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one 1080-12-2 10g $60 2021-12-16 Buy
TRC H533360 4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one 1080-12-2 5g $45 2021-12-16 Buy
Product number Packaging Price Buy
07551 5G-F $102 Buy
07551 5G $102 Buy
90609 100mg $69.5 Buy
H533360 10g $60 Buy
H533360 5g $45 Buy

Vanillylidenacetone Chemical Properties,Uses,Production

Description

Dehydrozingerone (1080-12-2) is a structural half analog of curcumin (Cat.# 10-1243) and is isolated from ginger rhizomes. Dehydrozingerone displays antioxidant, antibacterial and antifungal properties.1 It has also been shown to possess various antitumor effects2,3 and inhibit growth factor/peroxide-stimulated vascular smooth muscle function4.

Chemical Properties

Vanillylidene acetone has a very sweet, warm and tenacious odor.

Physical properties

Yellowish, needlelike crystals. Slightly soluble in water, soluble in alcohol and oils.

Uses

Vanillylidenacetone is one of ferulic acid derivatives. Studies have shown that vanillyl acetone has a certain inhibitory effect on Amaranthus, barnyardgrass, matang, dogwood and rape, among which the best inhibitory effect is on rape and Amaranthus.

Definition

ChEBI: Dehydrozingerone is a hydroxycinnamic acid.

Taste threshold values

Taste characteristics at 200 ppm: balsamic vanilla, with sweet aromatic spicy nuances.

References

1) Kubra et al. (2014), Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial compounds; J. Food Sci. Technol., 51 245 2) Motohashi et al. (1998), Inhibitory effects of dehydrozingerone and related compounds on 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation; Cancer Lett., 134 37 3) Yogosawa et al. (2012), Dehydrozingerone, a structural analog of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells; J. Nat. Prod., 75 2088 4) Liu et al. (2008), Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function; J. Cardiovasc. Pharmacol., 52 422

Vanillylidenacetone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 103)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21149 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30253 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34571 58
WinWin Chemical CO., Limited
+86-0577-64498589 +8615325081899 sales@win-winchemical.com China 14198 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9030 58
Henan Alfa Chemical Co., Ltd
+8618339805032 alfa4@alfachem.cn China 13141 58
sgtlifesciences pvt ltd
+8617013299288 dj@sgtlifesciences.com China 12382 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58

View Lastest Price from Vanillylidenacetone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Vanillylidene acetone  pictures 2020-02-26 Vanillylidene acetone
1080-12-2
US $0.00-0.00 / KG 100g 99.0%+ 100 tons Shaanxi Dideu Medichem Co. Ltd
VANILLYLIDENACETONE VANILLYLIDENEACETONE VANILLYLIDINE ACETONE FEMA 3738 DEHYDROZINGERONE 4-(4-hydroxy-3-methoxyphenyl)-3-buten-2-on dehydro(o)-paradol feruloylmethane 4-(4-HYDROXY-3-METHOXYPHENYL)-3-BUTEN-2-ONE 4-(4-HYDROXY-3-METHOXYPHENYL)-3-BUTENE-2-ONE 4-(4-HYDROXY-3-METHOXYPHENYL)BUT-3-EN-2-ONE methyl-3-methoxy-4-hydroxystyrylketone mhsk vanillalacetone Vanillideneacetone 3-Buten-2-one, 4-(4-hydroxy-3-methoxyphenyl)- 4-(3-Methoxy-4-hydroxyphenyl)-3-butene-2-one Dehydrogingerone Ferulic methyl ketone Vanillylideneacetone ,98% Dehydrozingerone Vanillylideneacetone 4-(4- hydroxy-3-Methoxyphenyl)-3- butene-2- ketone 4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one,predominantly trans Vanillylidenacetone >=98.5% 4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one> 4-(4-HYDROXY-3-METHOXYPHENYL)-3-BUTEN-2-ONE USP/EP/BP Vanilllylideneacetone 98%(Pre-trans) 4-(-HYDROXY-3-METHOXYPHENYL)-3-BUTEN-2-ONE 1080-12-2 1080-12-02 CH3COCHCHC6H3OCH3OH C11 to C12 Carbonyl Compounds Building Blocks Ketones Organic Building Blocks Aromatic Ketones (substituted)