5-Chloroindole
- CAS No.
- 17422-32-1
- Chemical Name:
- 5-Chloroindole
- Synonyms
- 5-CHLORO-1H-INDOLE;oroindoL;ChloroIndole;5-CHLOROINDOLE;5-CHLOROINDOLE99%;6-Chloroindole99%;5-Chloroindole 98%;5-Chloroindole >5-Chloroindole ,98%;1H-Indole,5-chloro-
- CBNumber:
- CB2126773
- Molecular Formula:
- C8H6ClN
- Molecular Weight:
- 151.59
- MDL Number:
- MFCD00005672
- MOL File:
- 17422-32-1.mol
- MSDS File:
- SDS
Melting point | 69-71 °C (lit.) |
---|---|
Boiling point | 130 °C / 0.4mmHg |
Density | 1.1976 (rough estimate) |
refractive index | 1.5437 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Soluble in alcohol. |
pka | 16.09±0.30(Predicted) |
form | Crystalline Powder |
color | White to slightly grayish-green |
BRN | 2651 |
InChIKey | MYTGFBZJLDLWQG-UHFFFAOYSA-N |
CAS DataBase Reference | 17422-32-1(CAS DataBase Reference) |
FDA UNII | FMJ30GB9J6 |
UNSPSC Code | 12352100 |
NACRES | NA.22 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 36/37/38-20/21/22 | |||||||||
Safety Statements | 22-24/25-36-26-37/39 | |||||||||
RIDADR | 2811 | |||||||||
WGK Germany | 3 | |||||||||
F | 10 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29339990 | |||||||||
NFPA 704 |
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5-Chloroindole price More Price(43)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C47604 | 5-Chloroindole 98% | 17422-32-1 | 1g | $44.58 | 2024-03-01 | Buy |
Sigma-Aldrich | C47604 | 5-Chloroindole 98% | 17422-32-1 | 5g | $80.4 | 2024-03-01 | Buy |
TCI Chemical | C1107 | 5-Chloroindole >98.0%(GC) | 17422-32-1 | 5g | $86 | 2024-03-01 | Buy |
TCI Chemical | C1107 | 5-Chloroindole >98.0%(GC) | 17422-32-1 | 25g | $254 | 2024-03-01 | Buy |
Usbiological | 006333 | 5-Chloroindole | 17422-32-1 | 2.5g | $446 | 2021-12-16 | Buy |
5-Chloroindole Chemical Properties,Uses,Production
Chemical Properties
White to slightly greyish-green crystalline powder
Uses
5-Chloroindole has been used in the synthesis of 5-chloro-3-indole-N,N- dimethylglyoxalamide and 5-chloro-N,N-dimethyltryptamine. It may be used in the synthesis of dyestuffs in the presence of biocatalysts. 5-Chloroindole can be synthesized by using 3-chlorobenzaldehyde as starting reagent
Uses
5-Chloroindole is a halo-substituted indole used in the preparation of neurologically active compounds such as atypical antipsychotic agents. 5-Chloroindole has been shown to depress serotonin levels in the brainstem and telencephalon.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 29, p. 1625, 1992 DOI: 10.1002/jhet.5570290644
The Journal of Organic Chemistry, 44, p. 578, 1979 DOI: 10.1021/jo01318a021
General Description
5-Chloroindole is a 5-substituted indole. It undergoes electropolymerization to form a redox-active film consisting of a cyclic trimer and chains of linked cyclic trimer (polymer). It is a potential positive allosteric modulator (PAM) of the 5-HT3 receptor. It has been reported as strong inhibitor of the copper dissolution in acidic sodium chloride solution. It has been tested as corrosion inhibitor of mild steel in 1N deaerated sulphuric acid. Synthesis of 5-chloroindole, via nitration of indoline has been described.
Purification Methods
It is distilled at high vacuum and recrystallises from pet ether (b 40-60o) or (b 80-100o) as glistening plates. The picrate has m 147o (146.5-147.5o)(from *C6H6). [Rydon & Tweddle J Chem Soc 3499 1955, Sugasawa J Org Chem 44 578 1979, Beilstein 20/4 V 34.]
5-Chloroindole Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18137 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 19825 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from 5-Chloroindole manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-04-15 | 5-Chloroindole
17422-32-1
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
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2025-04-04 | 5-Chloroindole
17422-32-1
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
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2020-06-02 | 5-Chloroindole in stock Factory
17422-32-1
|
US $1.00 / KG | 1KG | TOP 3 Factory in China | Top 3 largest production capacity Factory | Chemwill Asia Co.,Ltd. |
-
- 5-Chloroindole
17422-32-1
- US $0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 5-Chloroindole
17422-32-1
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 5-Chloroindole in stock Factory
17422-32-1
- US $1.00 / KG
- TOP 3 Factory in China
- Chemwill Asia Co.,Ltd.
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