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ChemicalBook >> CAS DataBase List >>11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine

11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine

11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine Structure
11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine structure
CAS No.
1977-07-7
Chemical Name:
11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
Synonyms
Dechloroclozapine;Dopamine serotonin antagonist-1;11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine;5H-Dibenzo[b,e][1,4]diazepine, 11-(4-methyl-1-piperazinyl)-;inhibit,Inhibitor,Muscarinic acetylcholine receptor,hM4Di,Deschloroclozapine,hM3Dq,muscarinic-based,mAChR,DREADDs;11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepineQ: What is 11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine Q: What is the CAS Number of 11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
CBNumber:
CB21316359
Molecular Formula:
C18H20N4
Molecular Weight:
292.38
MDL Number:
MFCD01730958
MOL File:
1977-07-7.mol
Last updated:2023-06-30 15:45:59
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11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine Properties

Boiling point 457.5±55.0 °C(Predicted)
Density 1.22±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO : ≥ 83.3 mg/mL (284.90 mM)
pka 7.82±0.20(Predicted)
form solid
color Yellow

11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-M3647 Deschloroclozapine 99.79% 1977-07-7 10mg $100 2021-12-16 Buy
ChemScene CS-M3647 Deschloroclozapine 99.79% 1977-07-7 50mg $350 2021-12-16 Buy
American Custom Chemicals Corporation CHM0997406 11-(4-METHYL-1-PIPERAZINYL)-5H-DIBENZO(B,E)(1,4)DIAZEPINE 95.00% 1977-07-7 5MG $496.91 2021-12-16 Buy
ChemScene CS-M3647 Deschloroclozapine 99.79% 1977-07-7 100mg $550 2021-12-16 Buy
Alichem 1977077 11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine 1977-07-7 100mg $780 2021-12-16 Buy
Product number Packaging Price Buy
CS-M3647 10mg $100 Buy
CS-M3647 50mg $350 Buy
CHM0997406 5MG $496.91 Buy
CS-M3647 100mg $550 Buy
1977077 100mg $780 Buy

11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine Chemical Properties,Uses,Production

Biological Activity

Deschloroclozapine is a potent, high-affinity, selective, metabolically stable agonist of muscarinic-based DREADDs.

in vitro

Deschloroclozapine has greater potencies for DREADDs than previous agonists in vitro. Deschloroclozapine is a potent agonist for hM 3 Dq with an EC 50 =0.13 nM. Deschloroclozapine is also a potent agonist for hM 4 Di with an EC 50 =0.081 nM.
Deschloroclozapine is a potent and selective agonist for hM 3 Dq and hM 4 Di, it does not display significant agonistic activity for any of the 318 tests wild-type GPCRs at <10 nM.

b>

target

Ki: 6.3 nM (hM 3 Dq), 4.2 nM (hM 4 Di)

storage

Room temperature

11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine Preparation Products And Raw materials

Raw materials

Preparation Products

11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai Hekang Biotechnology Co., Ltd. 18939837085 youchemicals@gmail.com China 1824 55
Bide Pharmatech Ltd. 400-1647117 15221909166 product02@bidepharm.com China 41438 60
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17995 56
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216 info@yuhaochemical.com China 2031 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9929 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 8256 55
Aikon International Limited 025-66113011 18112977050 cb6@aikonchem.com China 15495 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
LEAPCHEM CO., LTD. 		58
Aladdin Scientific 		58
Shanghai Hekang Biotechnology Co., Ltd. 55
Bide Pharmatech Ltd. 60
ChemStrong Scientific Co.,Ltd 56
HangZhou YuHao Chemical Technology Co., Ltd. 58
Shanghai Chaolan Chemical Technology Center 58
Hubei Yangxin Medical Technology Co., Ltd. 55
Aikon International Limited 58

1977-07-7(11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine)Related Search:

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11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine Dechloroclozapine 5H-Dibenzo[b,e][1,4]diazepine, 11-(4-methyl-1-piperazinyl)- 11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepineQ: What is 11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine Q: What is the CAS Number of 11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine Dopamine serotonin antagonist-1 inhibit,Inhibitor,Muscarinic acetylcholine receptor,hM4Di,Deschloroclozapine,hM3Dq,muscarinic-based,mAChR,DREADDs 1977-07-7