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lycaconitine

CAS No.
25867-19-0
Chemical Name:
lycaconitine
Synonyms
lycaconitine;4-[[[2-(2,5-Dioxo-1-pyrrolidinyl)benzoyl]oxy]methyl]-20-ethyl-1α,6β,14α,16β-tetramethoxyaconitane-7,8-diol;Aconitane-7,8-diol, 4-[[[2-(2,5-dioxo-1-pyrrolidinyl)benzoyl]oxy]methyl]-20-ethyl-1,6,14,16-tetramethoxy-, (1α,6β,14α,16β)-
CBNumber:
CB21327465
Molecular Formula:
C36H48N2O10
Molecular Weight:
668.77
MDL Number:
MOL File:
25867-19-0.mol
Last updated:2022-12-21 16:56:50

lycaconitine Properties

Melting point 111-114°
alpha D +42°; also reported as +31.5°
Boiling point 803.2±65.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
pka 12.18±0.70(Predicted)
FDA UNII T03UXI5O64

lycaconitine Chemical Properties,Uses,Production

Description

The literature concerning this alkaloid obtained from the roots of Aconitum lycoctonum is somewhat confusing. All workers agree that it is amorphous, weakly basic, and yields no crystalline derivatives. It is readily soluble in CHCl3, EtOH, C6H6 and CS2 but only slightly so in Et20 or H20. The original formula assigned to the base was C36H4601ON2, placing it in the aconitine group of ester alkaloids. On hydrolysis with boiling H20 or dilute HCl it has been stated to yield succinic acid and anthranoyllycoctonine whilst alkalies hydrolyze it to lycoctonic acid (succinylanthranilic acid) and lycoctonine for which the formulae C2sH3907N, C2oH330sN and more recently C2sH4107N have been proposed. The alternative formula of C27H3406N2, suggested by Kuzovkov and Platonova, appears to be erroneous in view of the hydrolysis products.

References

Dragendorff, Spohn.,Jahresb. Fortschr. Chern., 1394 (1884)
Marion, Manske., Can. J. Res., 24B, 1 (1946)
Kuzovkov, Platonova., J. Gen. Chern., USSR, 29, 2782 (1959)

lycaconitine Preparation Products And Raw materials

Raw materials

Preparation Products

lycaconitine Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21631 55
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 27313 60
4-[[[2-(2,5-Dioxo-1-pyrrolidinyl)benzoyl]oxy]methyl]-20-ethyl-1α,6β,14α,16β-tetramethoxyaconitane-7,8-diol lycaconitine Aconitane-7,8-diol, 4-[[[2-(2,5-dioxo-1-pyrrolidinyl)benzoyl]oxy]methyl]-20-ethyl-1,6,14,16-tetramethoxy-, (1α,6β,14α,16β)- 25867-19-0 C36H48N2O10