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physalin B

CAS No.
23133-56-4
Chemical Name:
physalin B
Synonyms
NSC-287088;physalin B;Physalin B, 10 mM in DMSO;(16S,25S)-14α,17α:14,27-Diepoxy-13,20,22α-trihydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5-diene-18,26-dioic acid 18,20:26,22-dilactone;(16S,22R,25S)-14α,17α:14,27-Diepoxy-13,20,22-trihydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5-diene-18,26-dioic acid 18,20:26,22-dilactone;17,3-(Epoxymethano)-1,17:2,6-dimethano-17H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,21(1H,8aH,10bH)-tetrone, 2,3,6,6a,9,10,10a,14,16,16a-decahydro-8a-hydroxy-2,6a,10b-trimethyl-, (1S,2S,3S,6R,6aS,8aR,10aS,10bR,16aR,17R,18aR)-
CBNumber:
CB21363823
Molecular Formula:
C28H30O9
Molecular Weight:
510.536
MDL Number:
MFCD09838651
MOL File:
23133-56-4.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:54

physalin B Properties

Density 1.51±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka 12.27±0.70(Predicted)
color Off-white to light yellow

physalin B price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation SHG0005817 PHYSALIN B 95.00% 23133-56-4 5MG $505.33 2021-12-16 Buy
Product number Packaging Price Buy
SHG0005817 5MG $505.33 Buy

physalin B Chemical Properties,Uses,Production

Uses

Physalin B, one of the major active steroidal constituents of Cape gooseberry, induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. Physalin B inhibits the ubiquitin-proteasome pathway and induces incomplete autophagic response in human colon cancer cells in vitro[1][2].

Definition

ChEBI: A physalin with antimalarial, antitumour and antimicrobial activities isolated from Physalis angulata.

References

[1] Wang A, et al. Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. Biomed Pharmacother. 2018;101:334-341. DOI:10.1016/j.biopha.2018.02.094
[2] Ma YM, et al. Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro. Acta Pharmacol Sin. 2015;36(4):517-527. DOI:10.1038/aps.2014.157

physalin B Preparation Products And Raw materials

Raw materials

Preparation Products

physalin B Suppliers

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897 sales@biopurify.com China 3772 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38630 58
Mensura Group Limited
+8618109034517 1058503172@qq.com China 2900 58
Shanghai Winherb Medical Technology Co., Ltd. 400-186-5138 13341702378 winherb@126.com China 1010 58
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6905 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29763 68
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12306 58
Chengdu Push Bio-Technology Co., Ltd. 028-85370565-229 18080489829 3004654993@qq.com China 8914 60

View Lastest Price from physalin B manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Physalin B pictures 2024-11-19 Physalin B
23133-56-4
US $362.00-1180.00 / mg 98.40% 10g TargetMol Chemicals Inc.
  • Physalin B pictures
  • Physalin B
    23133-56-4
  • US $362.00-1180.00 / mg
  • 98.40%
  • TargetMol Chemicals Inc.
physalin B (16S,22R,25S)-14α,17α:14,27-Diepoxy-13,20,22-trihydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5-diene-18,26-dioic acid 18,20:26,22-dilactone (16S,25S)-14α,17α:14,27-Diepoxy-13,20,22α-trihydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5-diene-18,26-dioic acid 18,20:26,22-dilactone 17,3-(Epoxymethano)-1,17:2,6-dimethano-17H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,21(1H,8aH,10bH)-tetrone, 2,3,6,6a,9,10,10a,14,16,16a-decahydro-8a-hydroxy-2,6a,10b-trimethyl-, (1S,2S,3S,6R,6aS,8aR,10aS,10bR,16aR,17R,18aR)- NSC-287088 Physalin B, 10 mM in DMSO 23133-56-4 C28H30O9