ChemicalBook >> CAS DataBase List >>J 113863
J 113863
- CAS No.
- 202796-41-6
- Chemical Name:
- J 113863
- Synonyms
- cis-J-113863
- CBNumber:
- CB213744245
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Last updated:2025-01-27 09:38:02
J 113863 Chemical Properties,Uses,Production
Biological Activity
J113863 is a high affinity antagonist for CCR1 and CCR3 receptors. Also both J113863 and its enantiomer c exhibit low binding affinity toward CCR2 and CCR5 where they activate three Gi and two G0 protein isoforms. J113863 does not activate G12 protein isoform. J113863 binding to CCR2 and CCR5 induce the recruitment of b-arrestin 2 whereas UCB35625 did not. J113863 and UCB35625 are biased ligands for the chemokine receptors CCR2 and CCR5.
J 113863 Preparation Products And Raw materials
Raw materials
Preparation Products
J 113863 Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5098 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19699 | 58 |
| R&D Systems, Inc | 18003437475 | rdname@qq.com | CHINA | 35705 | 58 |
| Supplier | Advantage |
|---|---|
| Aladdin Scientific | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
| R&D Systems, Inc | 58 |
cis-J-113863
202796-41-6