ChemicalBook >> CAS DataBase List >>pinane-thromboxane A2

pinane-thromboxane A2

CAS No.
71154-83-1
Chemical Name:
pinane-thromboxane A2
Synonyms
OHJIHGVLRDHSDV-PUYXBYOHSA-N;5-Heptenoic acid, 7-[(1S,2R,3R,5S)-3-[(1E,3R)-3-hydroxy-1-octen-1-yl]-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-, (5Z)-;(1S-(1alpha,2beta(Z),3alpha(1E,3S*),5alpha))-7-(3-(3-Hydroxy-1-octenyl)-6,6-dimethylbicyclo(3.1.1)hept-2-yl)-5-heptenoic acid
CBNumber:
CB21398968
Molecular Formula:
C24H40O3
Molecular Weight:
376.57
MDL Number:
MOL File:
71154-83-1.mol
Last updated:2025-04-17 18:22:24

pinane-thromboxane A2 Properties

storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): .15 mg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

pinane-thromboxane A2 price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10008510 15(R)-Pinane Thromboxane A2 >98% 71154-83-1 500μg $73 2024-03-01 Buy
Cayman Chemical 10008510 15(R)-Pinane Thromboxane A2 >98% 71154-83-1 1mg $138 2024-03-01 Buy
Cayman Chemical 10008510 15(R)-Pinane Thromboxane A2 >98% 71154-83-1 5mg $575 2024-03-01 Buy
Cayman Chemical 10008510 15(R)-Pinane Thromboxane A2 >98% 71154-83-1 10mg $1003 2024-03-01 Buy
AK Scientific 8515CP (Z)-7-[(1S,2R,5S)-3-[(E,3R)-3-Hydroxyoct-1-enyl]-6,6-dimethyl-2-bicyclo[3.1.1]heptanyl]hept-5-enoicacid 71154-83-1 10mg $1215 2021-12-16 Buy
Product number Packaging Price Buy
10008510 500μg $73 Buy
10008510 1mg $138 Buy
10008510 5mg $575 Buy
10008510 10mg $1003 Buy
8515CP 10mg $1215 Buy

pinane-thromboxane A2 Chemical Properties,Uses,Production

Description

15(R)-Pinane thromboxane A2 is the (R)-epimer of pinane thromboxane A2 (PTA2; ). 15(R)-PTA2 does not inhibit collagen-induced platelet aggregation (IC50s = 120-130 μM).1 It does not affect gastric tone in isolated rat gastric fundus when used at concentrations of 0.5 or 1.5 μg/ml and is less effective than PTA2 at inhibiting prostaglandin-induced contraction of isolated rat stomach muscle.2

Uses

15(R)-PTA2 (15(R)-Pinanethromboxane A2) is an antithrombotic agent that inhibits platelet aggregation. 15(R)-PTA2 inhibits stable prostaglandin endoperoxide analog-induced constriction of feline coronary arteries and stabilizes hepatic lysosomes. 15(R)-PTA2 also inhibits thromboxane synthase but has no effect on prostacyclin synthase[1].

References

1. Caton, M.P.L., Stuttle, K.A.J., Tuffin, D.P., et al. Comparative action of carbocyclic thromboxane A2 stereoisomers on platelets Eur. J. Med. Chem. 35(12),1099-1107(2000).
2. Bennett, A., and Sanger, G.J. Pinane thromboxane A2 analogues are non-selective prostanoid antagonists in rat and human stomach muscle Br. J. Pharmacol. 77(4),591-596(1982).

pinane-thromboxane A2 Preparation Products And Raw materials

Raw materials

Preparation Products

pinane-thromboxane A2 Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19725 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 233051 58

View Lastest Price from pinane-thromboxane A2 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
15(R)-Pinane Thromboxane A2 pictures 2024-10-28 15(R)-Pinane Thromboxane A2
71154-83-1
US $345.00-2500.00 / mg 10g TargetMol Chemicals Inc.
(1S-(1alpha,2beta(Z),3alpha(1E,3S*),5alpha))-7-(3-(3-Hydroxy-1-octenyl)-6,6-dimethylbicyclo(3.1.1)hept-2-yl)-5-heptenoic acid OHJIHGVLRDHSDV-PUYXBYOHSA-N 5-Heptenoic acid, 7-[(1S,2R,3R,5S)-3-[(1E,3R)-3-hydroxy-1-octen-1-yl]-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-, (5Z)- 71154-83-1