ChemicalBook >> CAS DataBase List >>Cyclosporin C

Cyclosporin C

CAS No.
59787-61-0
Chemical Name:
Cyclosporin C
Synonyms
CL246;WF-3484;CS-2545;CS-2546;CYCLOSPORIN C;Thr2-cyclosporine;Cyclosporin C, >=95%;Cyclosporine IMpurity-C;Cyclosporin Impurity C;Cyclosporine Impurity 3
CBNumber:
CB2153074
Molecular Formula:
C62H111N11O13
Molecular Weight:
1218.61
MDL Number:
MFCD06410945
MOL File:
59787-61-0.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

Cyclosporin C Properties

Melting point 144-1460C
alpha D20 -255° (c = 0.5 in chloroform); D20 -182° (c = 0.5 in methanol)
Boiling point 1316.0±65.0 °C(Predicted)
Density 1.033±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO: ≥10mg/mL
pka 13.06±0.70(Predicted)
form Colorless to off-white crystalline solid.
color White to Off-White
InChIKey JTOKYIBTLUQVQV-PCACHRFWSA-N
CAS DataBase Reference 59787-61-0
FDA UNII 6S744L5508

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H362-H350-H302
Precautionary statements  P264-P270-P301+P312-P330-P501-P201-P260-P263-P264-P270-P308+P313
WGK Germany  3
NFPA 704
0
2 0

Cyclosporin C price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29152 Cyclosporin C 59787-61-0 5mg $117 2024-03-01 Buy
Cayman Chemical 29152 Cyclosporin C 59787-61-0 25mg $330 2024-03-01 Buy
Cayman Chemical 29152 Cyclosporin C 59787-61-0 1mg $34 2024-03-01 Buy
Cayman Chemical 29152 Cyclosporin C 59787-61-0 10mg $183 2024-03-01 Buy
TRC C988905 Cyclosporin C 59787-61-0 5mg $265 2021-12-16 Buy
Product number Packaging Price Buy
29152 5mg $117 Buy
29152 25mg $330 Buy
29152 1mg $34 Buy
29152 10mg $183 Buy
C988905 5mg $265 Buy

Cyclosporin C Chemical Properties,Uses,Production

Description

Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. It is active against isolates of B. cinerea, A. niger, and Alternaria, Mucor, and Penicillium species (MICs = 0.1-5 μg/ml). Cyclosporin C (15 μg/ml) inhibits vaccinia virus replication in infected BSC40 cells by 98.82%. It inhibits lymphocyte proliferation induced by the mitogens concanavalin A (ConA; ), phytohemagglutinin L (PHA), and pokeweed mitogen (PWM), as well as proliferation induced by alloantigen in mixed lymphocyte culture when used at a concentration of 100 ng/ml. Cyclosporin C (100 ng/ml) inhibits the local graft versus host (GVH) reaction in mice receiving splenocyte grafts.

Chemical Properties

White Solid

Uses

A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Uses

Cyclosporin C is a minor analogue of the cyclosporin complex produced by a number of fungal species, including Trichoderma, Tolypocladium, Fusarium, Nectria and Acremonium. Cyclosporin C possesses immunosuppressant activity but has been much less extensively investigated than the major analogue, cyclosporin A.

storage

+4°C

Cyclosporin C Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 202)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou FandaChem Co.,Ltd.
+8615858145714 FandaChem@Gmail.com China 9087 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3772 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14332 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Shenzhen Excellent Biotech Co., Ltd.
13480692018 ramyan@ex-biotech.com CHINA 954 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 15319487004 1015@dideu.com China 3942 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58

View Lastest Price from Cyclosporin C manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cyclosporin C pictures 2024-11-19 Cyclosporin C
59787-61-0
US $446.00-1380.00 / mg 98.77% 10g TargetMol Chemicals Inc.
Cyclosporin C pictures 2023-05-26 Cyclosporin C
59787-61-0
US $0.00-0.00 / g 1g 95% 1kg Jiangsu Nata Opto-electronic Material Co.,Ltd.
Thr2-Cyclosporine pictures 2022-02-25 Thr2-Cyclosporine
59787-61-0
US $299.00 / KG 1KG 99% 1 ton Hong Kong Tiansheng New Material Trading Co., Ltd
  • Cyclosporin C pictures
  • Cyclosporin C
    59787-61-0
  • US $446.00-1380.00 / mg
  • 98.77%
  • TargetMol Chemicals Inc.
  • Cyclosporin C pictures
  • Cyclosporin C
    59787-61-0
  • US $0.00-0.00 / g
  • 95%
  • Jiangsu Nata Opto-electronic Material Co.,Ltd.
  • Thr2-Cyclosporine pictures
  • Thr2-Cyclosporine
    59787-61-0
  • US $299.00 / KG
  • 99%
  • Hong Kong Tiansheng New Material Trading Co., Ltd
CYCLOSPORIN C Thr2-cyclosporine Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl] (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Thr-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-) WF-3484 7-L-Threoninecyclosporin A Cyclosporine IMpurity-C 7-L-Threoninecyclosporin A, WF 3484 7-Threonine-cyclosporin A Cyclosporin C, >=95% Cyclosporine C/Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl] 30-(1-hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriaconta CS-2545 CS-2546 cyclo-[MeBmt-Thr-Sar-MeLeu-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal] Cyclosporine EP Impurity C CL246 Cyclosporin Impurity C Cyclosporin Impurity 3(Cyclosporin C) Cyclosporin A, 7-L-threonine- Cyclosporine Impurity 3 (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-((1R,2R,E)-1-Hydroxy-2-methylhex-4-en-1-yl)-30-((R)-1-hydroxyethyl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone (3R,6S,9S,12R,15R,18S,21R,24S,30R,33S)-30-(1-Hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,1 (3R,6S,9S,12R,15R,18S,21R,24S,30R,33S)-30-(1-Hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone Cyclosporin C, EvoPure? (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-30-[(1R)-1-hydroxyethyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone 59787-61-0 69787-61-0 59767-61-0 C62H111N11O13 Intermediates & Fine Chemicals Peptides Pharmaceuticals ACTIVE PHARMACEUTICAL INGREDIENTS