(R)-(-)-1-Cyclohexylethylamine
- CAS No.
- 5913-13-3
- Chemical Name:
- (R)-(-)-1-Cyclohexylethylamine
- Synonyms
- (R)-1-CYCLOHEXYLETHYLAMINE;(R)-1-Cyclohexylethanamine;(1R)-1-Cyclohexylethanamine;[(1R)-1-Cyclohexylethyl]amine;(R)-(-)-1-CYCLOHEXYLETHYLAMINE;(1R)-1-cyclohexylethan-1-amine;(R)-alpha-cyclohexanemethylamine;(R)-(-)-(1-Aminoethyl)cyclohexane;(R)-(-)-1-CYCLOHEXYLETHYLAMINE 98%;(R)-(-)-1-Cyclohexylethylamine >
- CBNumber:
- CB2170978
- Molecular Formula:
- C8H17N
- Molecular Weight:
- 127.23
- MDL Number:
- MFCD00043338
- MOL File:
- 5913-13-3.mol
- MSDS File:
- SDS
| Melting point | -15°C (estimate) |
|---|---|
| Boiling point | 177-178 °C (lit.) |
| alpha | -3.8 º (NEAT) |
| Density | 0.866 g/mL at 20 °C (lit.) |
| refractive index |
n |
| Flash point | 126 °F |
| pka | 10.89±0.29(Predicted) |
| form | clear liquid |
| color | Colorless to Almost colorless |
| optical activity | [α]20/D 4°, neat &_& [α]20/D -3.8±0.3°, neat |
| Water Solubility | Miscible with acetone, chloroform,dimethyl sulfoxide, ethanol, methanol, ether, petroleum ether and dichloromethane. Insoluble in water. |
| Sensitive | Air Sensitive |
| BRN | 2935070 |
| CAS DataBase Reference | 5913-13-3(CAS DataBase Reference) |
| NIST Chemistry Reference | R-(-)-Cyclohexylethylamine(5913-13-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H302+H312-H314 | |||||||||
| Precautionary statements | P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 10-21/22-34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 2734 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10-23 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 2921309990 | |||||||||
| NFPA 704 |
|
(R)-(-)-1-Cyclohexylethylamine price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 336505 | (R)-(?)-1-Cyclohexylethylamine 98% | 5913-13-3 | 5g | $136 | 2024-03-01 | Buy |
| TCI Chemical | C1541 | (R)-(-)-1-Cyclohexylethylamine >98.0%(GC)(T) | 5913-13-3 | 5g | $151 | 2024-03-01 | Buy |
| TCI Chemical | C1541 | (R)-(-)-1-Cyclohexylethylamine >98.0%(GC)(T) | 5913-13-3 | 25g | $431 | 2024-03-01 | Buy |
| Alfa Aesar | L19051 | (R)-(-)-1-Cyclohexylethylamine, ChiPros 98%, ee 94+% | 5913-13-3 | 1g | $23.65 | 2024-03-01 | Buy |
| Alfa Aesar | L19051 | (R)-(-)-1-Cyclohexylethylamine, ChiPros 98%, ee 94+% | 5913-13-3 | 5g | $51.65 | 2024-03-01 | Buy |
(R)-(-)-1-Cyclohexylethylamine Chemical Properties,Uses,Production
Chemical Properties
optical purity >99% ee
Uses
(R)-(-)-1-Cyclohexylethylamine may be used in the preparation of a chiral calix[4]arene Schiff base derivatives with potential enantioselective recognition ability towards amines.
Uses
(R)-(-)-1-Cyclohexylethylamine is used in the preparation of benzylidene(1-cyclohexylethyl)amine by reacting with benzaldehyde. It is also used to prepare chiral polymethacrylamides, which are employed as stationary phases for the liquid-chromatographic resolution of racemic amides. In addition to this, it is used in the preparation of polyamides bound to silica gel for high performance liquid chromatography, which are pressure-stable.
General Description
(R)-(-)-1-Cyclohexylethylamine is a chiral amine mainly used as a resolving agent for racemic compounds.
Purification Methods
Purify it by conversion to the bitartrate salt (m 172o), then decomposing with strong alkali and extracting into Et2O, drying (KOH), filtering, evaporating and distilling. The hydrochloride salt has m 242o (from EtOH/Et2O), [] D -5.0o (c 10 H2O, from (+) amine). The oxalate salt has m 132o (from H2O). The (±)-base has b 176-178o/760mm, and HCl has m 237-238o. [Reihlen et al. Justus Liebigs Ann Chem 532 247 1938, Leithe Chem Ber 65 660 1932, Beilstein 12 III 95.]
(R)-(-)-1-Cyclohexylethylamine Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-(-)-1-Cyclohexylethylamine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
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