ANTI-CASPASE-7
- CAS No.
- 189258-14-8
- Chemical Name:
- ANTI-CASPASE-7
- Synonyms
- MCH3;ICE-7;CASP7;CMH-1;LICE-2;ICE-LAP3;ANTI-MCH3;ANTI-ICE-7;ANTI-CASP7;MCH-3ALPHA
- CBNumber:
- CB2182142
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01633625
- MOL File:
- Mol file
ANTI-CASPASE-7 price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4503316 | Anti-CASP7 (p20, Cleaved-Asp198) antibody produced in rabbit affinity isolated antibody | 189258-14-8 | 100μg | $506 | 2024-03-01 | Buy |
| Sigma-Aldrich | PRS3467 | Anti-Caspase-7 (ab2) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 189258-14-8 | 100μG | $524 | 2024-03-01 | Buy |
| Sigma-Aldrich | C1104 | Monoclonal Anti-Caspase 7 antibody produced in rat clone 11E4, purified immunoglobulin, buffered aqueous solution | 189258-14-8 | 0.2mL | $214 | 2024-03-01 | Buy |
| Usbiological | 382199 | CASP7 | 189258-14-8 | 96Tests | $729 | 2021-12-16 | Buy |
| Usbiological | 382197 | CASP7 | 189258-14-8 | 96Tests | $729 | 2021-12-16 | Buy |
ANTI-CASPASE-7 Chemical Properties,Uses,Production
Uses
Monoclonal Anti-Caspase 7 antibody produced in rat is suitable for the following applications:
- Immunoprecipitation
- Microarray
- Western blotting at a concentration of 2-4μg/mL using a whole extract of cultured human acute T cell leukemia Jurkat cells.
General Description
Caspase-7 is a apoptosis-related cysteine peptidase, commonly known as CASP7. It is a human protein encoded by the CASP7 gene. CASP7 is a member of the caspase (cysteine aspartate protease) family of proteins and is an executioner protein of apoptosis.
Biochem/physiol Actions
Caspase-3 and -7 plays a central role in the execution-phase of cell apoptosis. The gene for caspase 7 (also known as Mch3, CMH-1 and ICELAP3) encodes a “short” prodomain protein product of 35 kDa that belongs to the Ced3/ICE family of cysteine proteases. Caspase 7 undergoes acleavage upon activation by caspase-3, -9 and -10, and granzyme B, leading to p20 and p12 subunits. It is an important intracellular effector of granzyme B-mediated apoptosis and cytotoxic Tlymphocyte- induced cell killing in vivo. Monoclonal antibodies reacting specifically with caspase 7 are useful tools for the study of protease networks involved in development and regulation and governing the life and death of cells and tissues.
ANTI-CASPASE-7 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-CASPASE-7 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Kanglang Biotechnology Co., Ltd. | 021-61998208 18217752821 | sales@klbio.cn | China | 9617 | 58 |
| Supplier | Advantage |
|---|---|
| Creative Enzymes | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |
| Sigma-Aldrich | 80 |
| Shanghai Kanglang Biotechnology Co., Ltd. | 58 |