2-Aminoisobutyric Acid
- CAS No.
- 62-57-7
- Chemical Name:
- 2-Aminoisobutyric Acid
- Synonyms
- AIB;2-Amino-2-methylpropanoic acid;H-AIB-OH;Aib-OH;L-Aib-OH;2-METHYLALANINE;N-ME-ALA-OH;N-ME-ALANINE;H-ALPHA-METHYLALANINE;α-Aminoisobutyric acid
- CBNumber:
- CB2182809
- Molecular Formula:
- C4H9NO2
- Molecular Weight:
- 103.12
- MDL Number:
- MFCD00008049
- MOL File:
- 62-57-7.mol
- MSDS File:
- SDS
| Melting point | ≥300 °C |
|---|---|
| Boiling point | 193.35°C (rough estimate) |
| Density | 1.1602 (rough estimate) |
| refractive index | 1.4183 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | Very easily soluble in water, poorly soluble in alcohol, insoluble in oils. |
| form | Crystalline Powder |
| pka | 2.36(at 25℃) |
| color | White |
| Odor | Practically odorless in the dry state |
| Water Solubility | SOLUBLE |
| Merck | 14,445 |
| BRN | 506496 |
| InChIKey | FUOOLUPWFVMBKG-UHFFFAOYSA-N |
| LogP | -0.163 (est) |
| CAS DataBase Reference | 62-57-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 1E7ZW41IQU |
| NIST Chemistry Reference | «alpha»-Aminoisobutanoic acid(62-57-7) |
| EPA Substance Registry System | Alanine, 2-methyl- (62-57-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AY7000000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29224995 | |||||||||
| NFPA 704 |
|
2-Aminoisobutyric Acid price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 850993 | 2-Aminoisobutyric acid 98% | 62-57-7 | 25g | $62.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | 850993 | 2-Aminoisobutyric acid 98% | 62-57-7 | 100g | $126 | 2024-03-01 | Buy |
| TCI Chemical | A0323 | 2-Aminoisobutyric Acid >98.0%(T) | 62-57-7 | 25g | $34 | 2024-03-01 | Buy |
| TCI Chemical | A0323 | 2-Aminoisobutyric Acid >98.0%(T) | 62-57-7 | 100g | $93 | 2024-03-01 | Buy |
| Alfa Aesar | A13021 | 2-Aminoisobutyric acid, 99% | 62-57-7 | 25g | $35.65 | 2024-03-01 | Buy |
2-Aminoisobutyric Acid Chemical Properties,Uses,Production
Applications
2-Methylalanine is an Alanine (A481400) derivative. Alanine is an amino acid that occurs naturally in nature. It is a functional component in the alanine cycle which regulates the level of alanine aminotransferases which can be used as a diagnostic tool to predict type II diabetes.
Description
2-Aminoisobutyric acid, also known as alpha-methylalanine or a-aminoisobutanoate, belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). 2-Aminoisobutyric acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. 2-Aminoisobutyric acid exists in all living organisms, ranging from bacteria to humans. Outside of the human body, 2-Aminoisobutyric acid has been detected, but not quantified in, milk (cow). This could make 2-aminoisobutyric acid a potential biomarker for the consumption of these foods. Aminoisobutyric acid is a nonprotein amino acid (is an end product of pyrimidine metabolism) excreted in the urine of about 5% of healthy individuals , and high excretion is an autosomal recessive phenotype.
source
2-aminoisobutyric acid is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin. With the exception of a few bacteria, it is non-metabolisable, and therefore used in bioassays. It derives from a propionic acid and an isobutyric acid.
Chemical Properties
White crystalline powder
Uses
2-Aminoisobutyric Acid inotransferases which can be used as a diagnostic tool to predict type II diabetes.
Uses
2-Aminoisobutyric acid is a non- protein amino acid present in some antibiotics. It acts as a strong helix inducer in peptides. It is non-metabolisable used in bioassays.
Definition
ChEBI: A rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin. With the exception of a few bacteria, it is non-metabolisable, and therefore used in bioassays.
Preparation
α-Aminoisobutyric Acid is prepared from Acetone (Blatt: Org. Synth. CoIl. vol. H, page 29, 1943) or by the Bucherer method (Org. Synth. vol. XX, 1940, page 42).
Synthesis Reference(s)
The Journal of Organic Chemistry, 29, p. 1148, 1964 DOI: 10.1021/jo01028a036
Solubility in organics
poorly soluble in alcohol, insoluble in oils.
Purification Methods
Crystallise the acid from aqueous EtOH and dry it at 110o. [Zelinski & Stadnikoff Chem Ber 39 1726 1906, Beilstein
2-Aminoisobutyric Acid Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 | daisy@enlaibio.com | China | 1106 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18751 | 58 |
| Taizhou Tianhong Biochemistry Technology Co., Ltd. | 0523-86132544 | sales@thbiochem.com | CHINA | 305 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
View Lastest Price from 2-Aminoisobutyric Acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-23 | Aib
62-57-7
|
US $0.00-0.00 / kg | 1kg | 99% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | |
 |
2024-12-13 | 2-Aminoisobutyric Acid
62-57-7
|
US $0.00 / Kg/Drum | 1KG | 99%min | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-10-11 | 2-Aminoisobutyric Acid
62-57-7
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- Aib
62-57-7
- US $0.00-0.00 / kg
- 99%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- 2-Aminoisobutyric Acid
62-57-7
- US $0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 2-Aminoisobutyric Acid
62-57-7
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
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