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CYCLOPIAZONIC ACID

CAS No.
83136-88-3
Chemical Name:
CYCLOPIAZONIC ACID
Synonyms
CPA;CYCLOPIAZONIC ACID;PENICILLIUM CYCLOPIUM;ALPHA CYCLOPIAZONIC ACID;CYCLOPIAZONIC ACID, PENICILLIUM CYCLOPIUM;(6AR,11AS,11BR)-REL-10-ACETYL-2,6,6A,7,11A,11B-HEXAHYDRO-7,7-DIMETHYL-9H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-9-ONE;6H-Pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indole-9,11(2H,7H)-dione, 6a,10,11a,11b-tetrahydro-10-(1-hydroxyethylidene)-7,7-dimethyl-, (6aR,10Z,11aS,11bR)-;(6AA, 10Z, 11AB, 11BA)-6A,7,11A,11B-TETRAHYDRO-10-(1-HYDROXYETHYLIDENE)-7,7- DIMETHYL-6H-PYRROLO [1',2':2,3]ISOINDOLO [4,5,6-CD]INDOLE-9,11 (2H,10H)-DIONE
CBNumber:
CB2207177
Molecular Formula:
C20H20N2O3
Molecular Weight:
336.38
MDL Number:
MFCD00167445
MOL File:
83136-88-3.mol
Last updated:2023-05-04 17:34:42

CYCLOPIAZONIC ACID Properties

Melting point 245-246 °C
storage temp. −20°C
solubility DMSO: soluble
form powder
color white to off-white
FDA UNII X9TLY4580Z

SAFETY

Risk and Safety Statements

Hazard Codes  T
Risk Statements  25
Safety Statements  36/37/39-45
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  UY8587000
Toxicity Cyclopiazonic acid is a natural contaminant of cheese, corn, and peanuts. Due to the lack of analytical methods for quantifying cyclopiazonic acid, the amount present in the food supply and the potential health risks are uncertain. Cyclopiazonic acid distributes widely in mammalian tissues, especially skeletal muscle, and produces equally diverse cytotoxicity. This toxicant shares many pharmacological properties with antipsychotic drugs including catalepsy, hypothermia, hypokinesia, ptosis, tremor, gait disturbance, sedation without loss of righting reflex, atypical convulsion, and increased barbiturate sleeping time. The mode of action of cyclopiazonic acid involves its role as an inhibitor of Ca-ATPase.

CYCLOPIAZONIC ACID price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 1235 Cyclopiazonic Acid, ≥98%(HPLC) 83136-88-3 10 $156 2021-12-16 Buy
Tocris 1235 Cyclopiazonic Acid, ≥98%(HPLC) 83136-88-3 50 $645 2021-12-16 Buy
Usbiological C8860-01 Cyclopiazonic Acid 83136-88-3 1mg $327 2021-12-16 Buy
Usbiological 255065 Cyclopiazonic acid 83136-88-3 10mg $428 2021-12-16 Buy
Biorbyt Ltd orb545961 Cyclopiazonic acid >98% 83136-88-3 25mg $430.1 2021-12-16 Buy
Product number Packaging Price Buy
1235 10 $156 Buy
1235 50 $645 Buy
C8860-01 1mg $327 Buy
255065 10mg $428 Buy
orb545961 25mg $430.1 Buy

CYCLOPIAZONIC ACID Chemical Properties,Uses,Production

Uses

Cyclopiazonic Acid is an inhibitor of endoplasmic reticulum Ca2+-ATPase.

Definition

ChEBI: Alpha-cyclopiazonic acid is a member of alpha-cyclopiazonic acids. It is a conjugate acid of an alpha-cyclopiazonate. It is a tautomer of a (6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one.

CYCLOPIAZONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

CYCLOPIAZONIC ACID Suppliers

Global( 20)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69

83136-88-3(CYCLOPIAZONIC ACID)Related Search:

ALPHA CYCLOPIAZONIC ACID CPA CYCLOPIAZONIC ACID CYCLOPIAZONIC ACID, PENICILLIUM CYCLOPIUM PENICILLIUM CYCLOPIUM (6AR,11AS,11BR)-REL-10-ACETYL-2,6,6A,7,11A,11B-HEXAHYDRO-7,7-DIMETHYL-9H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-9-ONE (6AA, 10Z, 11AB, 11BA)-6A,7,11A,11B-TETRAHYDRO-10-(1-HYDROXYETHYLIDENE)-7,7- DIMETHYL-6H-PYRROLO [1',2':2,3]ISOINDOLO [4,5,6-CD]INDOLE-9,11 (2H,10H)-DIONE 6H-Pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indole-9,11(2H,7H)-dione, 6a,10,11a,11b-tetrahydro-10-(1-hydroxyethylidene)-7,7-dimethyl-, (6aR,10Z,11aS,11bR)- 83136-88-3 Cell Signaling and Neuroscience Cell Biology BioChemical Intracellular Calcium Regulators Intracellular Calcium Signaling