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Ethyl 2-oxo-4-phenylbutyrate

CAS No.
64920-29-2
Chemical Name:
Ethyl 2-oxo-4-phenylbutyrate
Synonyms
KETO ESTER;ETHYL BENZYLPYRUVATE;Ethyl 2-oxy-butyrate;2-oxo-4-phenylhexanoate;2 - oxo -4 - ethyl benzene;ETHYL-2-OXO-4-PHENYLBUTRATE;Ethy 2-oxo-4-phenylbutyrate;Ethyl α-oxobenzenebutanoate;ETHYL 2-OXO-4-PHENYLBUTYRATE;Ethyl-2-oxo-4-pheny1Butyrate
CBNumber:
CB2207283
Molecular Formula:
C12H14O3
Molecular Weight:
206.24
MDL Number:
MFCD00037533
MOL File:
64920-29-2.mol
MSDS File:
SDS
Last updated:2024-12-05 15:39:15

Ethyl 2-oxo-4-phenylbutyrate Properties

Boiling point 132 °C/2 mmHg (lit.)
Density 1.091 g/mL at 25 °C (lit.)
refractive index n20/D 1.504(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Oil
color Colourless
BRN 2725083
CAS DataBase Reference 64920-29-2(CAS DataBase Reference)
FDA UNII 5YNU9LPT51

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  23-24/25-36/37-26
WGK Germany  3
NFPA 704
0
0 0

Ethyl 2-oxo-4-phenylbutyrate price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar B20148 Ethyl 2-oxo-4-phenylbutyrate, 90+% 64920-29-2 10g $42.65 2024-03-01 Buy
Alfa Aesar B20148 Ethyl 2-oxo-4-phenylbutyrate, 90+% 64920-29-2 50g $135.65 2024-03-01 Buy
TRC E925385 Ethyl 2-oxo-4-phenylbutyrate, 90+% 64920-29-2 25g $105 2021-12-16 Buy
American Custom Chemicals Corporation APN0000360 ETHYL 2-OXO-4-PHENYLBUTYRATE 95.00% 64920-29-2 1G $128.1 2021-12-16 Buy
AK Scientific J54157 Ethyl 2-oxo-4-phenylbutyrate 64920-29-2 100g $180 2021-12-16 Buy
Product number Packaging Price Buy
B20148 10g $42.65 Buy
B20148 50g $135.65 Buy
E925385 25g $105 Buy
APN0000360 1G $128.1 Buy
J54157 100g $180 Buy

Ethyl 2-oxo-4-phenylbutyrate Chemical Properties,Uses,Production

synthesis

Potassium tert-butoxide (4.3 g, 38.34 mmol) was added in 1 portion to a solution of the diester (8 g, 25.56 mmol) in toluene (80 mL) at 0 °C. After being stirred at the same temperature for 30 min, the reaction mixture was kept at room temperature overnight. Water (100 mL) was added, the phases were separated, and the aqueous phase was extracted with EtOAc (3 × 100 mL). The combined organic extracts  were dried and evaporated. The residue was purifified by flflash chromatography  eluting with EtOAc:light petroleum (1:9) to give 5.6 g (78%) of the keto-ester as an orange oil.

Chemical Properties

light yellow oily liquid

Uses

Ethyl 2-oxo-4-phenylbutyrate may be used in the synthesis of ethyl (R)-2-hydroxy-4-phenylbutyrate, an important chiral precursor for angiotensin-converting enzyme (ACE) inhibitor.

General Description

Ethyl 2-oxo-4-phenylbutyrate is an aliphatic α-ketoester. Bioreduction of ethyl 2-oxo-4-phenylbutyrate is reported to yield ethyl (R)-2-hydroxy-4-phenylbutanoate. The effect of ionic liquid on the asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate by Saccharomyces cerevisiae has been reported. Asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate using a bacterial reductase is reported. Enantioselective hydrogenation of ethyl 2-oxo-4-phenylbutyrate using homogeneous Rh-diphosphine and heterogeneous Pt/Al2O3-cinchona catalysts has been reported.

Global( 272)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12834 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5857 58
Hebei Weibang Biotechnology Co., Ltd
+8617732866630 bess@weibangbio.com China 18150 58
Shanghai Xinchem Co., Ltd.
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Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8497 58

View Lastest Price from Ethyl 2-oxo-4-phenylbutyrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl 2-oxo-4-phenylbutyrate pictures 2024-12-05 Ethyl 2-oxo-4-phenylbutyrate
64920-29-2
US $0.00 / kg 1kg 99% 1000kg Shanghai Joiny Pharmaceutical Co.,LTD
Ethyl 2-oxo-4-phenylbutyrate pictures 2024-10-28 Ethyl 2-oxo-4-phenylbutyrate
64920-29-2
US $0.00 / KG 1KG 99% 500000kg Hebei Weibang Biotechnology Co., Ltd
Ethyl 2-oxo-4-phenylbutyrate pictures 2024-10-25 Ethyl 2-oxo-4-phenylbutyrate
64920-29-2
US $40.00-5.00 / kg 1kg 0.99 15 tons Hebei Yanxi Chemical Co., Ltd.
4-PHENYL-2-OXOBUTYRIC ACID ETHYL ESTER 2-OXO-4-PHENYLBUTANOIC ACID ETHYL ESTER 2-OXO-4-PHENYLBUTYRIC ACID ETHYL ESTER BENZYLPYRUVIC ACID ETHYL ESTER ETHYL-2 OXO-4 PHENYL BUTANOATE ETHYL 2-OXO-4-PHENYLBUTYRATE Ethyl 2-oxo-4-phenylbutyrate (93%) Ethyl 2-oxo-4-phenylbutyrate 97% Benzenebutanoicacid,.alpha.-oxo-,ethylester ETHYL-2-OXO-4-PHENYLBUTRATE Ethyl 2-oxo-phenylbutrate (EOPB) Benzenebutanoic acid, a-oxo-, ethyl ester Ethyl 2-oxo-4-phenylbutyrate, 90+% α-Oxobenzenebutanoic acid ethyl ester α-Oxobenzenebutyric acid ethyl ester Ethy 2-oxo-4-phenylbutyrate Ethyl 2-oxo-4-phenylbutyrate (for ACEI) Ethyl 4-phenyl-2-oxobutanoate 2-oxo-4-phenylhexanoate Benzylpyruvic Acid Ethyl Ester Ethyl Benzylpyruvate 2-Oxo-4-phenylbutyric Acid Ethyl Ester 2 - oxo -4 - ethyl benzene Ethyl 2-oxo-4-phenylbutyrate (> Ethyl 2-oxo-4-phenylbutyrate USP/EP/BP TIANFU CHEM Ethyl 2-oxo-4-phenylbutyrate KETO ESTER ETHYL BENZYLPYRUVATE Ethyl α-oxobenzenebutanoate Benzenebutanoic acid, α-oxo-, ethyl ester Ethyl 2-oxy-butyrate BEChemicalbookNZYLPYRUVICACIDETHYLESTER Ethyl-2- oxyl-4-Phenyl Butyrate Ethyl-2-oxo-4-pheny1Butyrate 64920-29-2 6490-29-2 C6H5CH2CH2COCOOCH2CH3 Building Blocks Carbonyl Compounds C12 to C63 Esters Organic Building Blocks C12 to C63 Carbonyl Compounds Esters Aromatics Intermediates of Sertraline Pharmaceutical Intermediates Building Blocks C12 to C63 Carbonyl Compounds Chemical Synthesis Organic Building Blocks (intermediate of lisinopril ) 1