H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2
- CAS No.
- 111857-96-6
- Chemical Name:
- H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2
- Synonyms
- BIM 23042;BIM 23042 TFA;(D-2-Nal5,Cys6;BIM-23042, DC-13-217;H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2;(D-2-NAL5,CYS6·11,TYR7,D-TRP8,VAL10,2-NAL12)-SOMATOSTATIN;(D-2-NAL5,CYS6'11,TYR7,D-TRP8,VAL10,2-NAL12)-SOMATOSTATIN-14 (5-12) AMIDE;(D-2-Nal?,Cys?·??,Tyr?,D-Trp?,Val??,2-Nal??)-Somatostatin-14 (5-12) amide trifluoroacetate salt;L-Alaninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-3-(2-naphthalenyl)-, cyclic (2→7)-disulfide
- CBNumber:
- CB2221348
- Molecular Formula:
- C63H73N11O9S2
- Molecular Weight:
- 1192.45
- MDL Number:
- MFCD00237258
- MOL File:
- 111857-96-6.mol
H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Usbiological | 254761 | BIM 23042 | 111857-96-6 | 1mg | $389 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | PEP0004454 | BIM-23042 95.00% | 111857-96-6 | 5MG | $496.93 | 2021-12-16 | Buy |
ApexBio Technology | B5401 | BIM23042 | 111857-96-6 | 1mg | $219 | 2021-12-16 | Buy |
H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 Chemical Properties,Uses,Production
Biological Activity
ki: 49 ±14 nm for neuromedin b-induced endpoint in hunmbr cellsneuromedin b, a mammalian peptide of the bombesinlike peptide family sharing amino acid homology with its amphibian counterpart ranatensin, elicits a diverse array of biological responses in central and peripheral tissues. bim 23042 [d-nal-cys-tyr- d-trp-lys-val-cys-nal-nh2] is a selective neuromedin b antagonist.
in vitro
bim 23042 has a l00-fold greater affinity for bb1 receptors than bb2 receptors. the submaximal mobilisation observed with neuromedin b (1 nm) was abolished by bim 23042 but restored with a subsequently higher concentration of neuromedin b (1 μm). bim 23042 competitively inhibited neuromedin b-induced endpoint in hunmbr cells with a ki of 49 ±14 nm [1].
References
[1] ryan rr, taylor je, daniel jl, cowan a. pharmacological profiles of two bombesin analogues in cells transfected with human neuromedin b receptors. eur j pharmacol. 1996 jun 13;306(1-3):307-14.
H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18777 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10310 | 58 |
Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9237 | 58 |
Nanjing TGpeptide | +86-13347807150 +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2943 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5225 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42958 | 64 |
View Lastest Price from H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2022-10-12 | H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2
111857-96-6
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
- H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2
111857-96-6
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.