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Cefmetazole sodium

Cefmetazole sodium Structure
Cefmetazole sodium structure
CAS No.
56796-39-5
Chemical Name:
Cefmetazole sodium
Synonyms
C08104;Metafar;Cefmetazone;Cefmetazole-Na;Sodium cefmetazole;Cefmetazole sodium;CS-1170 sodium salt;Cefotetan Impurity 2;Cefmetazole Sodium Salt >Cefmetazole sodium USP/EP/BP
CBNumber:
CB2231321
Molecular Formula:
C15H18N7NaO5S3
Molecular Weight:
495.52
MDL Number:
MFCD00214260
MOL File:
56796-39-5.mol
Last updated:2024-11-17 08:48:38
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Cefmetazole sodium Properties

Melting point >130°C (dec.)
storage temp. Inert atmosphere,2-8°C
solubility H2O: soluble50mg/mL
form powder
color White to Off-White
Water Solubility Soluble in water
Sensitive Hygroscopic
Merck 14,1926
Stability Hygroscopic
InChIKey BITQGIOJQWZUPL-PBCQUBLHSA-M
CAS DataBase Reference 56796-39-5(CAS DataBase Reference)
FDA UNII 37Y9VR4W7A
NCI Drug Dictionary cefmetazole sodium

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H315-H317-H319-H334-H335
Precautionary statements  P280-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  36/37/38-42/43
Safety Statements  26-36
WGK Germany  2
RTECS  XI0372200
HS Code  2941.90.3000
Toxicity LD50 i.v. in rats: >5000 mg/kg (Masuda)

Cefmetazole sodium price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C6048 Cefmetazole sodium salt 56796-39-5 1g $128 2024-03-01 Buy
Sigma-Aldrich C6048 Cefmetazole sodium salt 56796-39-5 250mg $43 2023-06-20 Buy
TCI Chemical C3029 Cefmetazole Sodium Salt >97.0%(T) 56796-39-5 250mg $67 2024-03-01 Buy
TCI Chemical C3029 Cefmetazole Sodium Salt >97.0%(T) 56796-39-5 1g $237 2024-03-01 Buy
Alfa Aesar J66348 Cefmetazole sodium, 921 μg/mg 56796-39-5 1g $87.65 2024-03-01 Buy
Product number Packaging Price Buy
C6048 1g $128 Buy
C6048 250mg $43 Buy
C3029 250mg $67 Buy
C3029 1g $237 Buy
J66348 1g $87.65 Buy

Cefmetazole sodium Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Semi-synthetic antibiotic derived from Cephamycin. Antibacterial

Uses

Cefmetazole sodium is used clinically in combination with Tanreqing for the treatment of Pulmonary infections like Senile Emphysema and other acute bacterial infections.

Definition

ChEBI: An organic sodium salt that is the sodium salt of cefmetazole.

brand name

Zefazone (Pharmacia & Upjohn）.

Clinical Use

Cefmetazole (Zefazone) is a semisynthetic, third-generation,parenteral cephalosporin of the cephamycin group. Likeother cephamycins, the presence of the 7α-methoxyl groupconfers resistance to many β-lactamases. Cefmetazoleexhibits significantly higher potency against members ofthe Enterobacteriaceae family but lower activity againstBacteroides spp. than cefoxitin. It is highly active againstN. gonorrhoeae, including -lactamase–producing strains. Incommon with other cephamycins, cefmetazole is ineffectiveagainst indole-positive Proteus, Enterobacter, Providencia,Serratia, and Pseudomonas spp. Cefmetazole has the MTTmoiety associated with increased bleeding in certain highriskpatients. It has a plasma half-life of 1.1 hours.

Cefmetazole sodium Preparation Products And Raw materials

Raw materials

Preparation Products

Cefmetazole sodium Suppliers

Global( 228)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085 abby@weibangbio.com China 8810 58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		+8618092446649 sarah@tnjone.com China 1143 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Shandong chuangyingchemical Co., Ltd. 		18853181302 sale@chuangyingchem.com CHINA 5906 58
Shanghai Longyu Biotechnology Co., Ltd. 		+8619521488211 info@longyupharma.com China 2541 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Supplier Advantage
Hebei Weibang Biotechnology Co., Ltd 		58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		58
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Hubei xin bonus chemical co. LTD 		58
Shandong chuangyingchemical Co., Ltd. 		58
Shanghai Longyu Biotechnology Co., Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
TargetMol Chemicals Inc. 		58

View Lastest Price from Cefmetazole sodium manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cefmetazole sodium pictures 2024-12-13 Cefmetazole sodium
56796-39-5
 US $0.00 / KG/Tin 5KG 98%min 500kg WUHAN FORTUNA CHEMICAL CO., LTD
Cefmetazole sodium pictures 2024-11-16 Cefmetazole sodium
56796-39-5
 US $46.00 / mg 99.26% 10g TargetMol Chemicals Inc.
Cefmetazole sodium pictures 2024-11-16 Cefmetazole sodium
56796-39-5
 US $46.00 / mg 99.26% 10g TargetMol Chemicals Inc.

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1of4

Cefmetazone 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R-cis)- Cefmetazole-Na CS-1170 sodium salt Metafar Sodium cefmetazole (6R,7S)-7-[[2-[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl -1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene -2-carboxylic Acid Sodium Salt Cefmetazole sodium Sodium (6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (6R)-7-[[[(Cyanomethyl)thio]acetyl]amino]-7β-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt C08104 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[(cyanoMethyl)thio]acetyl]aMino]-7-Methoxy-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-,sodiuM salt (1:1), (6R,7S)- Cefotetan Impurity 1 Sodium Salt (Cefmetazole Sodium Salt) sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido sodium (6R,7S)-7-[[2-(cyanomethylthio)-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Cefotetan Impurity 2 Cefmetazole Sodium Salt > Cefmetazole sodium USP/EP/BP Sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 56796-39-5 59796-39-5 C15H16N7NaO5S3 C15H17N7O5S3 C15H16N7O5S3Na Sulfur & Selenium Compounds A - KAntibiotics Antibacterial Antibiotics A to Antibiotics A-FAntibiotics Chemical Structure Class Interferes with Cell Wall SynthesisAntibiotics Mechanism of Action Penicillins and Cephalosporins (beta-Lactams) Spectrum of Activity Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals