2-Hydroxy-3-[(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy]-4-methoxy-6-propylbenzoic acid
- CAS No.
- 607-11-4
- Chemical Name:
- 2-Hydroxy-3-[(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy]-4-methoxy-6-propylbenzoic acid
- Synonyms
- Sekikaic acid;2-Hydroxy-3-[(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy]-4-methoxy-6-propylbenzoic acid;Benzoic acid, 2-hydroxy-3-[(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy]-4-methoxy-6-propyl-
- CBNumber:
- CB22389604
- Molecular Formula:
- C22H26O8
- Molecular Weight:
- 418.44
- MDL Number:
- MOL File:
- 607-11-4.mol
2-Hydroxy-3-[(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy]-4-methoxy-6-propylbenzoic acid Chemical Properties,Uses,Production
Definition
ChEBI: Sekikaic acid is a carbonyl compound.
Biological Activity
Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities.1,2,3 It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 μM.1 Sekikaic acid is active against the rg recombinant strain of respiratory syncytial virus (RSV; IC50 = 5.69 μg/ml).2 It inhibits the protein-protein interaction between mixed lineage leukemia 1 (MLL1) and the GACKIX domain of CREB-binding protein (CBP; IC50 = 34 μM).3
References
1.Thadhani, V.M., Choudhary, M.I., Ali, S., et al.Antioxidant activity of some lichen metabolitesNat. Prod. Res.25(19)1827-1837(2011) 2.Lai, D., Odimegwu, D.C., Esimone, C., et al.Phenolic compounds with in vitro activity against respiratory syncytial virus from the Nigerian lichen Ramalina farinaceaPlanta Med.79(15)1440-1446(2013) 3.Majmudar, C.Y., H?jfeldt, J.W., Arevang, C.J., et al.Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300Angew. Chem. Int. Ed. Engl.51(45)11258-11262(2012)
2-Hydroxy-3-[(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy]-4-methoxy-6-propylbenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Hydroxy-3-[(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy]-4-methoxy-6-propylbenzoic acid Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1249 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 28091 | 58 |
Supplier | Advantage |
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BOC Sciences | 65 |
Shanghai EFE Biological Technology Co., Ltd. | 58 |
Beijing Biocreative Technology Co., Ltd. | 58 |
TargetMol Chemicals Inc. | 58 |