2'-deoxy-2'-fluoro-2'-C-methylcytidine
- CAS No.
- 817204-33-4
- Chemical Name:
- 2'-deoxy-2'-fluoro-2'-C-methylcytidine
- Synonyms
- ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate;PSI 6130;R 1656;CS-1995;PSI-6130;PSI 6130;Sofosbuvir Impurity 121;PSI-6130;R 1656;PSI 6130;2'-Deoxy-2'-F-2'-C-methylcytidine;2'-deoxy-2'-Fluoro-2'-methylcytidine;2'-deoxy-2'-fluoro-2'-C-methylcytidin
- CBNumber:
- CB22525888
- Molecular Formula:
- C10H14FN3O4
- Molecular Weight:
- 259.23
- MDL Number:
- MFCD13176566
- MOL File:
- 817204-33-4.mol
- MSDS File:
- SDS
Melting point | 216-218℃ |
---|---|
Boiling point | 482.4±55.0 °C(Predicted) |
Density | 1.67 |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | Methanol (Slightly), Water (Slightly) |
pka | 12.86±0.70(Predicted) |
form | Solid |
color | White to Light Brown |
Stability | Hygroscopic |
FDA UNII | 05J68784G1 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
2'-deoxy-2'-fluoro-2'-C-methylcytidine price More Price(22)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 13575 | PSI-6130 | 817204-33-4 | 1mg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 13575 | PSI-6130 | 817204-33-4 | 5mg | $321 | 2024-03-01 | Buy |
TRC | P839680 | PSI6130 | 817204-33-4 | 25mg | $640 | 2021-12-16 | Buy |
Matrix Scientific | 097930 | 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 95+% | 817204-33-4 | 1g | $685 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146167 | PSI6130 >99% | 817204-33-4 | 1g | $765 | 2021-12-16 | Buy |
2'-deoxy-2'-fluoro-2'-C-methylcytidine Chemical Properties,Uses,Production
Description
PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV; Ki = 4.3 μM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC50s = 0.51 and 0.30 μM, respectively). PSI-6130 also inhibits replication of HCV GT-1b and GT-1a replicons from clinical isolates, with EC50 values ranging from 0.60 to 1.41 μM, and 0.20 to 0.43 μM, respectively, in the same assay. It has little or no activity against West Nile Virus (WNV), Dengue type 2 virus (DV), human immunodeficiency virus (HIV), or hepatitis B virus (HBV; EC90s = 46.3, >100, >100, and >10 μM, respectively).
Uses
PSI-6130 is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B.
target
Hepatitis C Virus Nucleoside
2'-deoxy-2'-fluoro-2'-C-methylcytidine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20294 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 | sales@unisyn.cn | CHINA | 332 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
View Lastest Price from 2'-deoxy-2'-fluoro-2'-C-methylcytidine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-03-23 | 2'-deoxy-2'-fluoro-2'-C-methylcytidine
817204-33-4
|
US $5.00-0.10 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
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2019-08-06 | 2'-deoxy-2'-fluoro-2'-C-methylcytidine
817204-33-4
|
US $5.00 / KG | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- 2'-deoxy-2'-fluoro-2'-C-methylcytidine
817204-33-4
- US $5.00-0.10 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2'-deoxy-2'-fluoro-2'-C-methylcytidine
817204-33-4
- US $5.00 / KG
- 99%
- Career Henan Chemical Co
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