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2'-deoxy-2'-fluoro-2'-C-methylcytidine

2'-deoxy-2'-fluoro-2'-C-methylcytidine structure

CAS No.: 817204-33-4

Chemical Name:: 2'-deoxy-2'-fluoro-2'-C-methylcytidine

Synonyms: ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate;PSI 6130;R 1656;CS-1995;PSI-6130(R 1656);PSI-6130;PSI 6130;Sofosbuvir Impurity 121;PSI-6130;R 1656;PSI 6130;2'-Deoxy-2'-F-2'-C-methylcytidine;2'-deoxy-2'-Fluoro-2'-methylcytidine

CBNumber:: CB22525888

Molecular Formula:: C10H14FN3O4

Molecular Weight:: 259.23

MDL Number:: MFCD13176566

MOL File:: 817204-33-4.mol

MSDS File:: SDS

Last updated:2024-11-19 23:02:33

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2'-deoxy-2'-fluoro-2'-C-methylcytidine Properties

Melting point	216-218℃
Boiling point	482.4±55.0 °C(Predicted)
Density	1.67
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	Methanol (Slightly), Water (Slightly)
pka	12.86±0.70(Predicted)
form	Solid
color	White to Light Brown
Stability	Hygroscopic
FDA UNII	05J68784G1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

2'-deoxy-2'-fluoro-2'-C-methylcytidine price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	13575	PSI-6130	817204-33-4	1mg	$93	2024-03-01	Buy
Cayman Chemical	13575	PSI-6130	817204-33-4	5mg	$321	2024-03-01	Buy
TRC	P839680	PSI6130	817204-33-4	25mg	$640	2021-12-16	Buy
Matrix Scientific	097930	4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 95+%	817204-33-4	1g	$685	2021-12-16	Buy
Biorbyt Ltd	orb146167	PSI6130 >99%	817204-33-4	1g	$765	2021-12-16	Buy

Product number	Packaging	Price	Buy
13575	1mg	$93	Buy
13575	5mg	$321	Buy
P839680	25mg	$640	Buy
097930	1g	$685	Buy
orb146167	1g	$765	Buy

2'-deoxy-2'-fluoro-2'-C-methylcytidine Chemical Properties,Uses,Production

Description

PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV; K_i = 4.3 μM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC₅₀s = 0.51 and 0.30 μM, respectively). PSI-6130 also inhibits replication of HCV GT-1b and GT-1a replicons from clinical isolates, with EC₅₀ values ranging from 0.60 to 1.41 μM, and 0.20 to 0.43 μM, respectively, in the same assay. It has little or no activity against West Nile Virus (WNV), Dengue type 2 virus (DV), human immunodeficiency virus (HIV), or hepatitis B virus (HBV; EC₉₀s = 46.3, >100, >100, and >10 μM, respectively).

Uses

PSI-6130 is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B.

target

Hepatitis C Virus Nucleoside

2'-deoxy-2'-fluoro-2'-C-methylcytidine Preparation Products And Raw materials

Raw materials

Preparation Products

2'-deoxy-2'-fluoro-2'-C-methylcytidine Suppliers

Global( 134)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20285	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18774	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29881	58
Nanjing Baifuli Technology Co., Ltd.	+86-15335185688	sales@unisyn.cn	CHINA	332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Nanjing Baifuli Technology Co., Ltd.	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 2'-deoxy-2'-fluoro-2'-C-methylcytidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-19	PSI-6130 817204-33-4	US $57.00-219.00 / mg		99.36%	10g	TargetMol Chemicals Inc.
2024-03-23	2'-deoxy-2'-fluoro-2'-C-methylcytidine 817204-33-4	US $5.00-0.10 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2019-08-06	2'-deoxy-2'-fluoro-2'-C-methylcytidine 817204-33-4	US $5.00 / KG	1KG	99%	1ton	Career Henan Chemical Co

PSI-6130
817204-33-4
US $57.00-219.00 / mg
99.36%
TargetMol Chemicals Inc.

2'-deoxy-2'-fluoro-2'-C-methylcytidine
817204-33-4
US $5.00-0.10 / KG
99%
Henan Fengda Chemical Co., Ltd

2'-deoxy-2'-fluoro-2'-C-methylcytidine
817204-33-4
US $5.00 / KG
99%
Career Henan Chemical Co

817204-33-4(2'-deoxy-2'-fluoro-2'-C-methylcytidine)Related Search:

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(2'R)-2'-deoxy-2'-fluoro-2'-methyl-Cytidine PSI-6130;R 1656;PSI 6130 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyr 2'-deoxy-2'-fluoro-2'-C-methylcytidine R 1656 ethyl 4-broMo-1-Methyl-pyrrole-2-carboxylate 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimi 4-AMino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidin-2(1H)-one R 1656; R-1656; R1656; PSI6130; PSI 6130 2'-deoxy-2'-fluoro-2'-C-methylcytidin 2'-Deoxy-2'-F-2'-C-methylcytidine CS-1995 PSI-6130;PSI 6130 Cytidine, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)- 2'-deoxy-2'-fluoro-2'-C-methylcytidine,817204-33-4 ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate PSI 6130 2'-deoxy-2'-Fluoro-2'-methylcytidine 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one (sofosbuvir Impurity) Sofosbuvir Impurity 121 2'-C-methyl-2'-Fluoro-2'-deoxyCytidine 2'-Deoxy-2'-fluoro-2'-C-methylcytidine PSI-6130(R 1656) 817204-33-4 apis