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Tylvalosin tartrate

Tylvalosin tartrate structure

CAS No.: 63428-13-7

Chemical Name:: Tylvalosin tartrate

Synonyms: Tylvalosin Tartrate;Acetylisovaleryltylosin Tartrate;Acetylisovaleryltylosin Tartrat;Tylosin, 3-acetate 4B-(3-methylbutanoate), (2R,3R)-2,3-dihydroxybutanedioate (salt);Aivlosin Tartrate;Tawanthin tartrate;TYLVALOSIN TARTRATE PREMIX;Acetylisovalerylosin tartrate;Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate;TIANFU-CHEM Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate 63428-13-7

CBNumber:: CB22534581

Molecular Formula:: C57H93NO25

Molecular Weight:: 1192.35

MDL Number:: MFCD31656805

MOL File:: 63428-13-7.mol

Last updated:2024-05-18 08:51:57

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Tylvalosin tartrate Properties

Melting point	208 - 211°C
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
Stability	Hygroscopic
InChIKey	OLLSDNUHBJHKJS-YZBHKUDENA-N
FDA UNII	AL5667FY0W

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501

NFPA 704

	0
2		0

Tylvalosin tartrate price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0099515	Tylvalosintartrate	63428-13-7	25mg	$50	2021-12-16	Buy
Matrix Scientific	097240	Acetylisovaleryltylosin tartrate 80%	63428-13-7	500mg	$95	2021-12-16	Buy
AK Scientific	9668AB	Acetylisovaleryltylosintartrate	63428-13-7	1g	$145	2021-12-16	Buy
American Custom Chemicals Corporation	API0019489	ACETYLISOVALERYLTYLOSIN TARTRATE 95.00%	63428-13-7	1G	$284.55	2021-12-16	Buy
AK Scientific	J50036	Acetylisovaleryltylosintartrate,tech.	63428-13-7	5g	$298	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0099515	25mg	$50	Buy
097240	500mg	$95	Buy
9668AB	1g	$145	Buy
API0019489	1G	$284.55	Buy
J50036	5g	$298	Buy

Tylvalosin tartrate Chemical Properties,Uses,Production

Uses

Tylvalosin Tartrate is an impurity of Tylvalosin (T898210); Tylvalosin is an anti-bacterial agent that is shown through study as a good inhibitor of gram-positive bacteria.

Pharmacokinetics

Tylvalosin tartrate is a macrolide antibiotic with antibacterial activity against Gram-positive and some Gram-negative organisms and mycoplasma. It acts by inhibiting protein synthesis in the bacterial cell. Macrolide antibiotics are metabolites or semi-synthetic derivatives of metabolites of soil organisms obtained by fermentation. They have differently-sized lactone rings and are essential due to the dimethylamino group. Tylvalosin has a sixteen-membered ring. Macrolides interfere with protein synthesis by reversibly binding to the 50S ribosome subunit.

Pharmacology

Tylvalosin tartrate is rapidly absorbed after oral administration of Aivlosin. After administration of the recommended dose, lung concentrations of 0.060–0.066 μg/ml were found at 2 and 12 hours post-treatment. The parent compound is widely distributed in the tissues, with the highest concentrations found in the lungs, bile, intestinal mucosa, spleen, kidney, and liver. There is evidence that the concentration of macrolides is higher at the site of infection than in plasma, particularly in neutrophils, alveolar macrophages, and alveolar epithelial cells. In vitro metabolism studies have confirmed that the parent compound is rapidly metabolised to 3-O-acetyltylosin. In a trial with 14C-labeled Aivlosin administered at 2.125 mg/kg to pigs for 7 days, over 70% of the dose was excreted in the feces, with urinary excretion accounting for 3 to 4% of the dose.

in vitro

Tylvalosin tartrate (10 μg/mL; 0.5, 1 h) increases caspase-3 cleavage in porcine neutrophils, leading to DNA fragmentation during apoptosis.Tylvalosin tartrate (0.1-10 μg/mL; 0.5 h) Promote endocytosis of porcine neutrophils by macrophages without changing phagocytosis.

Tylvalosin tartrate Preparation Products And Raw materials

Raw materials

Preparation Products

Tylvalosin tartrate Suppliers

Global( 185)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Suikang Pharmaceutical Co.,Ltd.	+86-18239973690 +86-18239973690	sales@suikangpharm.com	China	186	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12470	58
shandong perfect biotechnology co.ltd	+86-53169958659; +8618596095638	sales@sdperfect.com	China	294	58
ARCTIC EXPORTS INC	+1-3026880818 +1-3026880818	ARCTICEXPORTSINC@GMAIL.COM	Canada	68	58
airuikechemical co., ltd.	+undefined86-15315557071	sales05@airuikechemical.com	China	994	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618740459177	sarah@tnjone.com	China	1142	58
Apeloa production Co.,Limited	+86-19131931000 +86-19131931000	admin@apcl.com.cn	China	246	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15956	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58

Supplier	Advantage
Henan Suikang Pharmaceutical Co.,Ltd.	58
Hebei Mojin Biotechnology Co., Ltd	58
shandong perfect biotechnology co.ltd	58
ARCTIC EXPORTS INC	58
airuikechemical co., ltd.	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
Apeloa production Co.,Limited	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58

View Lastest Price from Tylvalosin tartrate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-05-24	Tylvalosin tartrate 63428-13-7	US $1.00 / g	1g	98%	1000	Apeloa production Co.,Limited
2024-05-23	Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate 63428-13-7	US $0.00 / kg	25kg	98%	10tons	Henan Suikang Pharmaceutical Co.,Ltd.
2024-04-16	Tylvalosin Tartrate 63428-13-7	US $0.00-0.00 / kg	1kg	800U/mg;CVP	500	Hebei ZB Gamay Biological Technology Co.,Ltd

Tylvalosin tartrate
63428-13-7
US $1.00 / g
98%
Apeloa production Co.,Limited

Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate
63428-13-7
US $0.00 / kg
98%
Henan Suikang Pharmaceutical Co.,Ltd.

Tylvalosin Tartrate
63428-13-7
US $0.00-0.00 / kg
800U/mg;CVP
Hebei ZB Gamay Biological Technology Co.,Ltd

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Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate Aivlosin Tartrate (2S,3S,4R,6S)-6-(((2R,3S,4R,5R,6R)-6-(((4R,5S,6S,7R,9R,11E,13E,15R,16R)-4-acetoxy-16-ethyl-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl)oxy)-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl 3-methylbutanoate (2R,3R)-2,3-dihydroxysuccinic acid (2R,3R,4R,5R,6R)-6-(((2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-(((2S,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-5-Acetoxy-4-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl)methoxy)-4,5-dimethoxy-2-methyltetrahydro-2H-pyran-3-yl 3-methylbutanoate (2R,3R)-2,3-dihydroxysuccinate (2R,3R,4R,5R,6R)-6-(((2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-(((2S,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-5-Acetoxy-4-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-14-hydroxy-5,9,13-trimeth Tylvalosin TartrateQ: What is Tylvalosin Tartrate Q: What is the CAS Number of Tylvalosin Tartrate Q: What is the storage condition of Tylvalosin Tartrate Tawanthin tartrate TIANFU-CHEM Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate 63428-13-7 Acetylisovaleryltylosin Tartrate Tylvalosin Tartrate TYLVALOSIN TARTRATE PREMIX Tylosin, 3-acetate 4B-(3-methylbutanoate), (2R,3R)-2,3-dihydroxybutanedioate (salt) Acetylisovaleryltylosin Tartrat Acetylisovalerylosin tartrate 63428-13-7 C53H87NO19xC4H6O6 C57H93NO25 C53H87NO19C4H6O6 API