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PF 184

PF 184 structure

CAS No.: 1187460-81-6

Chemical Name:: PF 184

Synonyms: PF 184;8-[[[5-Chloro-2-[3,4-diMethyl-3,4-bis(hydroxyMethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]aMino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxaMide;1H-Benz[g]indazole-3-carboxamide, 8-[[[2-[3,4-bis(hydroxymethyl)-3,4-dimethyl-1-pyrrolidinyl]-5-chloro-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-

CBNumber:: CB22535689

Molecular Formula:: C32H32ClFN6O4

Molecular Weight:: 619.09

MDL Number:: MFCD17166976

MOL File:: 1187460-81-6.mol

Last updated:2023-06-30 15:45:59

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PF 184 Properties

Boiling point	790.6±60.0 °C(Predicted)
Density	1.47±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble to 100 mM in DMSO
form	Powder
pka	10.20±0.20(Predicted)

PF 184 price More Price(9)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	4238	PF184 ≥98%(HPLC)	1187460-81-6	10	$331	2021-12-16	Buy
TRC	P293750	PF184	1187460-81-6	1mg	$165	2021-12-16	Buy
Usbiological	019312	PF 184	1187460-81-6	10mg	$502	2021-12-16	Buy
American Custom Chemicals Corporation	API0010308	8-[[[5-CHLORO-2-[3,4-DIMETHYL-3,4-BIS(HYDROXYMETHYL)-1-PYRROLIDINYL]-4-PYRIDINYL]CARBONYL]AMINO]-1-(4-FLUOROPHENYL)-4,5-DIHYDRO-1H-BENZ[G]INDAZOLE-3-CARBOXAMIDE 95.00%	1187460-81-6	10MG	$716.1	2021-12-16	Buy
American Custom Chemicals Corporation	API0010308	8-[[[5-CHLORO-2-[3,4-DIMETHYL-3,4-BIS(HYDROXYMETHYL)-1-PYRROLIDINYL]-4-PYRIDINYL]CARBONYL]AMINO]-1-(4-FLUOROPHENYL)-4,5-DIHYDRO-1H-BENZ[G]INDAZOLE-3-CARBOXAMIDE 95.00%	1187460-81-6	25MG	$779.63	2021-12-16	Buy

Product number	Packaging	Price	Buy
4238	10	$331	Buy
P293750	1mg	$165	Buy
019312	10mg	$502	Buy
API0010308	10MG	$716.1	Buy
API0010308	25MG	$779.63	Buy

PF 184 Chemical Properties,Uses,Production

Uses

PF 184 is a potent and selective IKK-2 inhibitor (IC50 = 37 nM). Displays selectivity over 85 other kinases. Inhibits IL-1β-induced TNF-α in a steroid-insensitive in vitro model of oxidative stress.

storage

Store at +4°C

PF 184 Preparation Products And Raw materials

Raw materials

Preparation Products

PF 184 Suppliers

Global( 30)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	94837	76
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	56057	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4370	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.com	China	24246	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
J & K SCIENTIFIC LTD.	76
Chemsky (shanghai) International Co.,Ltd	60
EMMX Biotechnology LLC	60
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
MedBioPharmaceutical Technology Inc	58
TargetMol Chemicals Inc.	58
Nantong QuanYi Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58

PF 184 8-[[[5-Chloro-2-[3,4-diMethyl-3,4-bis(hydroxyMethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]aMino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxaMide 1H-Benz[g]indazole-3-carboxamide, 8-[[[2-[3,4-bis(hydroxymethyl)-3,4-dimethyl-1-pyrrolidinyl]-5-chloro-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro- 1187460-81-6 C32H32ClFN6O4 Amines Aromatics Heterocycles Inhibitors Intermediates & Fine Chemicals Pfizer Compounds Pharmaceuticals