Peramivir Trihydrate
- CAS No.
- 1041434-82-5
- Chemical Name:
- Peramivir Trihydrate
- Synonyms
- PeraMivir Hydrate;eraMivir;S-021812;Preamivir;BCX-1812,RWJ-270201;Rapiacta trihydrate;BCX 1812 trihydrate;Peramivir Trihydrate;Peramivir Tirhydrate;Peramivir Impurity A
- CBNumber:
- CB22538918
- Molecular Formula:
- C15H30N4O5
- Molecular Weight:
- 346.43
- MDL Number:
- MFCD22417093
- MOL File:
- 1041434-82-5.mol
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
---|---|
solubility | H2O : 6.6 mg/mL (17.26 mM; Need ultrasonic) |
form | Powder |
color | White to off-white |
InChIKey | DLIKIAYLVAIOME-KAJZLETJNA-N |
SMILES | [C@H]([C@]1([H])[C@@H]([C@@H](C(=O)O)C[C@H]1NC(N)=N)O)(NC(=O)C)C(CC)CC.O |&1:0,1,3,4,9,r| |
FDA UNII | QW7Y7ZR15U |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H317-H319 |
Precautionary statements | P280-P305+P351+P338 |
Peramivir Trihydrate price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML2486 | Peramivir trihydrate ≥98% (HPLC) | 1041434-82-5 | 5mg | $102 | 2024-03-01 | Buy |
Sigma-Aldrich | SML2486 | Peramivir trihydrate ≥98% (HPLC) | 1041434-82-5 | 25mg | $411 | 2024-03-01 | Buy |
ChemScene | CS-0732 | Peramivir trihydrate 99.40% | 1041434-82-5 | 50mg | $450 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0019040 | BCX-1812 TRIHYDRATE 95.00% | 1041434-82-5 | 5MG | $505.4 | 2021-12-16 | Buy |
ChemScene | CS-0732 | Peramivir trihydrate 99.40% | 1041434-82-5 | 5mg | $80 | 2021-12-16 | Buy |
Peramivir Trihydrate Chemical Properties,Uses,Production
Uses
Peramivir Trihydrate is a trihydrate of the anti-infection agent Peramivir Trihydrate which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.[1] The IC50 for Peramivir Trihydrate
Definition
ChEBI: A hydrate that is the trihydrate form of peramivir. Used for the treatment of acute uncomplicated influenza in patients 18 years and older who have been symptomatic for no more than two days.
in vitro
Peramivir trihydrate (0.3125-40 μM, 4 h) has nontoxicity to macrophage.
Peramivir trihydrate (2-10 μM, 6-12 h) inhibits cytokine release in LPS-induced hPBMCs.
in vivo
Peramivir trihydrate (20-60 mg/kg, i.p., single dose) inhibits LPS-induced cytokine storm, attenuates acute lung injury and prolongs the survival in cytokine storm syndrome model mice.
Peramivir trihydrate (75 mg/kg, i.m., once a day for 7 days) rescued BALB scid mice from lethal challenge with BR/08 in immunocompromised murine models of infuenza B virus infection.
Peramivir Trihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15352 | 58 |
Protheragen-ING | +16313385890 | info@protheragen-ing.com | United States | 3868 | 58 |
Jinan Jianfeng Chemical Co., Ltd | 0531-88110457; +8615562555968 | info@pharmachemm.com | China | 248 | 58 |
Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 998 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3002 | 58 |
View Lastest Price from Peramivir Trihydrate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-28 | Peramivir
1041434-82-5
|
US $0.00-0.00 / kg | 1kg | 99% | 1ton | Jinan Jianfeng Chemical Co., Ltd | ||
2024-11-27 | Peramivir trihydrate
1041434-82-5
|
US $0.00 / Kg/Bag | 10g | 99min HPLC | 10kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-11-19 | Peramivir Trihydrate
1041434-82-5
|
US $39.00-105.00 / mg | ≥95% | 10g | TargetMol Chemicals Inc. |
- Peramivir
1041434-82-5
- US $0.00-0.00 / kg
- 99%
- Jinan Jianfeng Chemical Co., Ltd
- Peramivir trihydrate
1041434-82-5
- US $0.00 / Kg/Bag
- 99min HPLC
- WUHAN FORTUNA CHEMICAL CO., LTD
- Peramivir Trihydrate
1041434-82-5
- US $39.00-105.00 / mg
- ≥95%
- TargetMol Chemicals Inc.