Myo-Inositol Trispyrophosphate HexasodiuM Salt
- CAS No.
- 23103-35-7
- Chemical Name:
- Myo-Inositol Trispyrophosphate HexasodiuM Salt
- Synonyms
- ITPP;ITTP HexasodiuM Salt;Myo-Inositol Tripyrphosphate HexasodiuM salt;Myo-Inositol Trispyrophosphate HexasodiuM Salt;Myo-Inositol Trispyrophosphate HexasodiuM Salt 9;MYO-INOSITOL TRISPYROPHOSPHATE HEXASODIUM (ITPP);Inositol cyclic-1,2:3,4:5,6-tris(P,P'-dihydrogen diphosphate) hexasodium salt;Myo-Inositol Cyclic 1,2:3,4:5,6-Tris(dihydrogen pyrophosphate)) HexasodiuM Salt;Myo-Inositol Cyclic 1,2:3,4:5,6-Tris(P,P'-dihydrogen diphosphate) HexasodiuM Salt
- CBNumber:
- CB22551061
- Molecular Formula:
- C6H13NaO21P6
- Molecular Weight:
- 629.98
- MDL Number:
- MFCD28899029
- MOL File:
- 23103-35-7.mol
- MSDS File:
- SDS
Myo-Inositol Trispyrophosphate HexasodiuM Salt price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | I666020 | myo-InositolTrispyrophosphateHexasodiumSalt | 23103-35-7 | 10mg | $185 | 2021-12-16 | Buy |
Usbiological | 293797 | myo-Inositol trispyrophosphate hexasodium salt | 23103-35-7 | 2g | $358 | 2021-12-16 | Buy |
TRC | I666020 | myo-InositolTrispyrophosphateHexasodiumSalt | 23103-35-7 | 100mg | $1455 | 2021-12-16 | Buy |
Biosynth Carbosynth | MI16762 | myo-Inositol trispyrophosphate hexasodium salt | 23103-35-7 | 25mg | $600 | 2021-12-16 | Buy |
Biosynth Carbosynth | MI16762 | myo-Inositol trispyrophosphate hexasodium salt | 23103-35-7 | 10mg | $300 | 2021-12-16 | Buy |
Myo-Inositol Trispyrophosphate HexasodiuM Salt Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
A novel membrane-permeant allosteric effector of hemoglobin (Hb), enhances the regulated oxygen release capacity of red blood cells, thus counteracting the effects of hypoxia in diseases such as cancer and cardiovascular ailments.
in vivo
Non-salt dose:
myo-Inositol trispyrophosphate (1.5 g/kg; intraperitoneal injection; twice a week for 4 weeks) has a protective effect in rat model of myocardial infarction[1].
myo-Inositol trispyrophosphate (1.5 g/kg; intravenous injection; once a week for 11 weeks) has antitumor activity in a rat model of pancreatic cancer[2].
Animal Model: | Male Wistar rats (280-320 g) with myocardial infarction[1] |
Dosage: | 1.5 g/kg (Non-salt dose) |
Administration: | Intraperitoneal injection (i.p.); twice a week for 4 weeks |
Result: | Essentially halted the increase of LV dilation and significantly reduced impairment of LV ejection fraction, while it had no effect on sham-operated rats. |
Animal Model: | DSL-6A/C1 tumors treated immunocompetent male Lewis rats[2] |
Dosage: | 1.5 g/kg (Non-salt dose) |
Administration: | Intravenous injection (i.v.); once a week for 11 weeks |
Result: | Significantly extended the survival time of rats. Basically did not cause liver metastasis and primary tumor growth was restricted to 2 cm3. Restored the pO2 pressure in tumors reducing hypoxia-inducible and proangiogenic factors. |
Myo-Inositol Trispyrophosphate HexasodiuM Salt Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 902 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15395 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
R&D Scientific Inc. | +1-2266000236 | sales@rdscientific.com | Canada | 1759 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 |
Supplier | Advantage |
---|---|
Henan Tianfu Chemical Co.,Ltd. | 55 |
Biochempartner | 58 |
BOC Sciences | 58 |
TopScience Biochemical | 58 |
AFINE CHEMICALS LIMITED | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | 58 |
LEAPCHEM CO., LTD. | 58 |
R&D Scientific Inc. | 58 |
Aladdin Scientific | 58 |
Aladdin Scientific | 58 |