ChemicalBook >> CAS DataBase List >>2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-

2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-

CAS No.
875787-07-8
Chemical Name:
2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
Synonyms
CS-758;LXR623;WAY 252623;LXR623/LXR-623;LXR-623 (WAY-252623);WAY-252623;LXR623;LXR 623;WAY252623;WAY 252623;2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-;2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)indazole;2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole;2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
CBNumber:
CB22626329
Molecular Formula:
C21H12ClF5N2
Molecular Weight:
422.78
MDL Number:
MFCD16495812
MOL File:
875787-07-8.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Properties

Melting point 93℃
Boiling point 528.4±50.0 °C(Predicted)
Density 1.40
storage temp. room temp
solubility DMSO:50.0(Max Conc. mg/mL);118.26(Max Conc. mM)
Ethanol:52.0(Max Conc. mg/mL);123.0(Max Conc. mM)
pka -1.87±0.30(Predicted)
form powder
color white to beige
FDA UNII 4W82FEU838

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
RIDADR  UN 2811 6.1 / PGIII
NFPA 704
0
2 0

2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PZ0257 WAY-252623 ≥98% (HPLC) 875787-07-8 5MG $118 2024-03-01 Buy
Sigma-Aldrich PZ0257 WAY-252623 ≥98% (HPLC) 875787-07-8 25MG $462 2024-03-01 Buy
Cayman Chemical 21117 LXR-623 ≥98% 875787-07-8 1mg $32 2024-03-01 Buy
Cayman Chemical 21117 LXR-623 ≥98% 875787-07-8 5mg $100 2024-03-01 Buy
Cayman Chemical 21117 LXR-623 ≥98% 875787-07-8 10mg $184 2024-03-01 Buy
Product number Packaging Price Buy
PZ0257 5MG $118 Buy
PZ0257 25MG $462 Buy
21117 1mg $32 Buy
21117 5mg $100 Buy
21117 10mg $184 Buy

2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Chemical Properties,Uses,Production

Uses

WAY 252623 is a novel and potent LXR (liverX receptor) β-agonist used as a potential candidate for the treatment of atopic dermatitis.

Biochem/physiol Actions

WAY-252623 (LXR623) is an orally available, potent and highly selective Liver X receptors (LXRs) agonist that significantly reduced total and LDL-cholesterol. WAY-252623 reduces lesion progression in the murine LDLR(-/-) atherosclerosis model.

storage

Store at +4°C

2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Spectrum

875787-07-8(2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-)Related Search:

2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- LXR623 2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole WAY 252623 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- 2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole WAY 252623 LXR623/LXR-623 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)indazole WAY-252623;LXR623;LXR 623;WAY252623;WAY 252623 CS-758 LXR-623 (WAY-252623) 875787-07-8 C21H12ClF5N2 Inhibitor Inhibitors API