ChemicalBook >> CAS DataBase List >>Urea, N'-(4,5,6,11,12,13-hexahydro-2-Methyl-4-oxo-11-propyl-2H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-8-yl)-N-Methyl-N-phenyl-

Urea, N'-(4,5,6,11,12,13-hexahydro-2-Methyl-4-oxo-11-propyl-2H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-8-yl)-N-Methyl-N-phenyl-

Urea, N'-(4,5,6,11,12,13-hexahydro-2-Methyl-4-oxo-11-propyl-2H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-8-yl)-N-Methyl-N-phenyl- structure

CAS No.: 856692-39-2

Chemical Name:: Urea, N'-(4,5,6,11,12,13-hexahydro-2-Methyl-4-oxo-11-propyl-2H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-8-yl)-N-Methyl-N-phenyl-

Synonyms: CEP-14083;DRYABXKGCXCACQ-UHFFFAOYSA-N;Urea, N'-(4,5,6,11,12,13-hexahydro-2-Methyl-4-oxo-11-propyl-2H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-8-yl)-N-Methyl-N-phenyl-

CBNumber:: CB22628505

Molecular Formula:: C31H30N6O2

Molecular Weight:: 518.6089

MDL Number:: MFCD18782698

MOL File:: 856692-39-2.mol

Last updated:2023-03-31 09:12:58

Request For Quotation

Urea, N'-(4,5,6,11,12,13-hexahydro-2-Methyl-4-oxo-11-propyl-2H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-8-yl)-N-Methyl-N-phenyl- Properties

Boiling point	833.7±65.0 °C(Predicted)
Density	1.40±0.1 g/cm3(Predicted)
pka	13.95±0.20(Predicted)

Urea, N'-(4,5,6,11,12,13-hexahydro-2-Methyl-4-oxo-11-propyl-2H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-8-yl)-N-Methyl-N-phenyl- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	CHM0293062	N'-(4,5,6,11,12,13-HEXAHYDRO-2-METHYL-4-OXO-11-PROPYL-2H-INDAZOLO-[5,4-A]PYRROLO-[3,4-C]CARBAZOL-8-YL)-N-METHYL-N-PHENYL-UREA 95.00%	856692-39-2	5MG	$501.63	2021-12-16	Buy

Product number	Packaging	Price	Buy
CHM0293062	5MG	$501.63	Buy

Urea, N'-(4,5,6,11,12,13-hexahydro-2-Methyl-4-oxo-11-propyl-2H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-8-yl)-N-Methyl-N-phenyl- Chemical Properties,Uses,Production

Description

CEP-14083 is a potent ALK inhibitor that has shown activity in an NPM/ALK?–carrying T-cell lymphoma in vitro study. Presumably, this compound binds to the hinge region of the kinase in an ATP-competitive manner. CEP-14083 displays a potent activity against ALK in enzymatic assays (IC50 = 11 nmol/L). Further, CEP-14083 is also able to inhibit the insulin receptor at a concentration within a nanomolar range. In a preclinical assay, CEP-14083 showed that, via NPM/ALK TK inhibition, it could control the expression of molecules that determine T-cell identity and signaling in lymphoma cells. CEP-14083 has shown preclinical activity in both cell lines and animal models harboring ALK alteration.

Urea, N'-(4,5,6,11,12,13-hexahydro-2-Methyl-4-oxo-11-propyl-2H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-8-yl)-N-Methyl-N-phenyl- Preparation Products And Raw materials

Raw materials

Preparation Products

Urea, N'-(4,5,6,11,12,13-hexahydro-2-Methyl-4-oxo-11-propyl-2H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-8-yl)-N-Methyl-N-phenyl- Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	--	info@bocsci.com	USA	0	65
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19696	58

Supplier	Advantage
BOC Sciences	65
TargetMol Chemicals Inc.	58

Urea, N'-(4,5,6,11,12,13-hexahydro-2-Methyl-4-oxo-11-propyl-2H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-8-yl)-N-Methyl-N-phenyl- DRYABXKGCXCACQ-UHFFFAOYSA-N CEP-14083 856692-39-2