2-Methoxyphenylboronic acid
- CAS No.
- 5720-06-9
- Chemical Name:
- 2-Methoxyphenylboronic acid
- Synonyms
- (2-Methoxyphenyl)boranediol;2-METHOXYBENZENEBORONIC ACID;DK766;0/9/20;AKOS BRN-0014;2-Boronoanisole;RARECHEM AH PB 0181;2-Methoxyphenylboron;o-Anisylboronic acid;Elagolix Impurity 46
- CBNumber:
- CB2264149
- Molecular Formula:
- C7H9BO3
- Molecular Weight:
- 151.96
- MDL Number:
- MFCD00236047
- MOL File:
- 5720-06-9.mol
- MSDS File:
- SDS
| Melting point | 105-110 °C (lit.) |
|---|---|
| Boiling point | 319.3±44.0 °C(Predicted) |
| Density | 1.17±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| pka | 8.55±0.58(Predicted) |
| form | Crystals or Crystalline Powder |
| color | Off-white |
| Water Solubility | Insoluble in water. |
| BRN | 3030981 |
| InChI | InChI=1S/C7H9BO3/c1-11-7-5-3-2-4-6(7)8(9)10/h2-5,9-10H,1H3 |
| InChIKey | ROEQGIFOWRQYHD-UHFFFAOYSA-N |
| SMILES | B(C1=CC=CC=C1OC)(O)O |
| CAS DataBase Reference | 5720-06-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 37/39-26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | No | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
2-Methoxyphenylboronic acid price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 445231 | 2-Methoxyphenylboronic acid 95% | 5720-06-9 | 1g | $18.16 | 2024-03-01 | Buy |
| Sigma-Aldrich | 445231 | 2-Methoxyphenylboronic acid 95% | 5720-06-9 | 5g | $61.2 | 2024-03-01 | Buy |
| TCI Chemical | M1261 | 2-Methoxyphenylboronic Acid (contains varying amounts of Anhydride) | 5720-06-9 | 1g | $18 | 2024-03-01 | Buy |
| TCI Chemical | M1261 | 2-Methoxyphenylboronic Acid (contains varying amounts of Anhydride) | 5720-06-9 | 5g | $24 | 2024-03-01 | Buy |
| Alfa Aesar | B21071 | 2-Methoxybenzeneboronic acid, 97% | 5720-06-9 | 1g | $36.65 | 2024-03-01 | Buy |
2-Methoxyphenylboronic acid Chemical Properties,Uses,Production
Description
2-Methoxyphenylboronic acid is an arylboronic acid. Arylboronic acids can be widely used as safe and environmentally friendly new aromatization reagents for scientific research and production of various fine chemicals containing aryl structures, such as pharmaceuticals, pesticides, and advanced materials. The reactions of arylboronic acids with halogenates play a pivotal role in today's drug synthesis, and such reactions were pioneered by Japanese scientists Suzuki's team, which won the Nobel Prize in Chemistry in 2010.
Chemical Properties
white to light yellow crystal powder
Uses
2-Methoxylphenylboronic acid is a phenylboronic acid used to investigate boron function in plants. It is used in Suzuki reaction, organic reaction that is classified as a coupling reaction where the coupling partners are a boronic acid with a halide catalyzed by a palladium(0) complex.
Preparation
Under the protection of nitrogen, add magnesium (2.9 g, 1.2 times) and tetrahydrofuran (20 ml) and dibromoethane (1.9 g) to a 250 ml three-necked flask with a dropping funnel; then add 2-methoxybromobenzene (17.1 g, 0.1 mol), trimethyl borate (36.8 g, 3.5 times) and tetrahydrofuran (50 ml) as solvent to the dropping funnel. Heat to 40 ℃, activate the magnesium powder, and then slowly add the mixture in the dropping funnel dropwise, control the speed to the reaction temperature does not exceed 60 ℃, add the reaction after stirring until the magnesium basically disappeared, and then heat the reflux reaction for 6 hours. Stop heating, cool to room temperature, hydrolyze with 5% dilute hydrochloric acid to pH<2. Distillation to recover THF solvent, as the solvent is reduced, the product precipitated; cooling and filtration, recrystallization in methanol/water can be obtained 2-methoxyphenylboronic acid.
2-Methoxyphenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
| Hebei Maison Chemical Co.,Ltd. | +8615511852758 | sales@maisonchem.com.cn | China | 484 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615350851019 | admin@86-ss.com | China | 1001 | 58 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18751 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 | |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| Beijing Green Guardee Technology Co., Ltd | 86-010-69706062 | sales2@greenguardee.com | CHINA | 650 | 58 |
View Lastest Price from 2-Methoxyphenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-23 | 2-Methoxyphenylboronic acid
5720-06-9
|
US $999.00-800.00 / ton | 1ton | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2023-05-04 | 2-Methoxyphenylboronic acid
5720-06-9
|
US $48.00-40.00 / KG | 1KG | 99% | 200tons | Guangzhou Sunton Biotechnology Co., Ltd. | |
 |
2023-03-08 | 2-Methoxyphenylboronic acid
5720-06-9
|
US $0.00-0.00 / kg | 0.1kg | 99% | 5MT | Zhuoer Chemical Co., Ltd |
-
- 2-Methoxyphenylboronic acid
5720-06-9
- US $999.00-800.00 / ton
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 2-Methoxyphenylboronic acid
5720-06-9
- US $48.00-40.00 / KG
- 99%
- Guangzhou Sunton Biotechnology Co., Ltd.
-
- 2-Methoxyphenylboronic acid
5720-06-9
- US $0.00-0.00 / kg
- 99%
- Zhuoer Chemical Co., Ltd