AZ 876
- CAS No.
- 898800-26-5
- Chemical Name:
- AZ 876
- Synonyms
- AZ 876;AZ 12260493;AZ-12260493.;AZ-876, AZ12260493;AZ876;AZ-876;AZ 876;AZ 876,Liver X receptor,AZ-876,LXR,Inhibitor,AZ876,inhibit;AZ876; AZ 876; AZ-876, AZ12260493; AZ 12260493; AZ-12260493.;2-tert-butyl-1,1-dioxo-5-phenyl-4-(4-piperidin-1-ylanilino)-1,2-thiazol-3-one;2-(tert-Butyl)-5-phenyl-4-((4-(piperidin-1-yl)phenyl)amino)isothiazol-3(2H)-one 1,1-dioxide;2-(1,1-Dimethylethyl)-5-phenyl-4-[[4-(1-piperidinyl)phenyl]amino]-3(2H)-isothiazolone 1,1-dioxide
- CBNumber:
- CB22667414
- Molecular Formula:
- C24H29N3O3S
- Molecular Weight:
- 439.57
- MDL Number:
- MFCD30377191
- MOL File:
- 898800-26-5.mol
AZ 876 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-5724 | AZ876 99.89% | 898800-26-5 | 1mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-5724 | AZ876 99.89% | 898800-26-5 | 5mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-5724 | AZ876 99.89% | 898800-26-5 | 10mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-5724 | AZ876 99.89% | 898800-26-5 | 50mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-5724 | AZ876 99.89% | 898800-26-5 | 100mg | $450 | 2021-12-16 | Buy |
AZ 876 Chemical Properties,Uses,Production
Uses
AZ876 is a potent and high-affinity LXR agonist. AZ876 displays 25-fold and 2.5-fold more potent than GW3965 (HY-10627) on human (h)LXRα and hLXRβ respectively[1][2].
References
[1] Cannon MV et al. The liver X receptor agonist AZ876 protects against pathological cardiac hypertrophy and fibrosis without lipogenic side effects. Eur J Heart Fail. 2015 Mar;17(3):273-82. DOI:10.1002/ejhf.243
[2] van der Hoorn J et al. Low dose of the liver X receptor agonist, AZ876, reduces atherosclerosis in APOE*3Leiden mice without affecting liver or plasma triglyceride levels. Br J Pharmacol. 2011 Apr;162(7):1553-63. DOI:10.1111/j.1476-5381.2010.01168.x
AZ 876 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Chemia Biotechnology（Shanghai） Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
