Kif15-IN-1
- CAS No.
- 672926-32-8
- Chemical Name:
- Kif15-IN-1
- Synonyms
- Kif15-IN-1;Kif15 inhibitor 1;Kif-15-IN-1,Kif15IN1,Kif15 IN 1;2-[[(2S)-2-(1,4-Dihydro-2,4-dioxo-3(2H)-quinazolinyl)-3-methyl-1-oxobutyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester;5-Thiazolecarboxylic acid, 2-[[(2S)-2-(1,4-dihydro-2,4-dioxo-3(2H)-quinazolinyl)-3-methyl-1-oxobutyl]amino]-4-methyl-, ethyl ester
- CBNumber:
- CB22685926
- Molecular Formula:
- C20H22N4O5S
- Molecular Weight:
- 430.48
- MDL Number:
- MFCD28167755
- MOL File:
- 672926-32-8.mol
Kif15-IN-1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | B3280 | Kif15-IN-1 | 672926-32-8 | 2mg | $341 | 2021-12-16 | Buy |
| ChemScene | CS-2697 | Kif15-IN-1 99.53% | 672926-32-8 | 5mg | $420 | 2021-12-16 | Buy |
| ApexBio Technology | B3280 | Kif15-IN-1 | 672926-32-8 | 5mg | $513 | 2021-12-16 | Buy |
| ApexBio Technology | B3280 | Kif15-IN-1 | 672926-32-8 | 10mg | $733 | 2021-12-16 | Buy |
| ChemScene | CS-2697 | Kif15-IN-1 99.53% | 672926-32-8 | 50mg | $1800 | 2021-12-16 | Buy |
Kif15-IN-1 Chemical Properties,Uses,Production
Biological Activity
kif15-in-1, a potent kif15 kinesin inhibitor; inhibits cellular proliferation in various tumor cell lines [1].kif15,also known as kinesin-12 and hklp2, is a motor protein expressed in all cells during mitosis and in postmitotic neurons undergoing axon growth [2]. kif15 is a kinesin-related protein whose mitotic homologues are believed to crosslink and immobilize spindle microtubules.kif15 is involved in maintaining bipolar microtubulespindle apparatusin dividing cells and shares redundant functions with kif11 [3].
References
[1]. preparation of quinazolinediones as kif15 kinesin inhibitors for treating cellular proliferative disorders. pat. appl. publ. (2004), us 20040053948 a1 20040318.
[2]. buster d w, baird d h, yu w, et al. expression of the mitotic kinesin kif15 in postmitotic neurons: implications for neuronal migration and development[j]. journal of neurocytology, 2003, 32(1): 79-96.
[3]. vanneste d, takagi m, imamoto n, et al. the role of hklp2 in the stabilization and maintenance of spindle bipolarity[j]. current biology, 2009, 19(20): 1712-1717.
Kif15-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
Kif15-IN-1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
| Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 | 505721671@qq.com | China | 3868 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4662 | 60 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |