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VJ115
- CAS No.
- 929256-79-1
- Chemical Name:
- VJ115
- Synonyms
- VJ115;1-Azabicyclo[2.2.2]octan-3-ol, 2-[[1-(phenylmethyl)-1H-indol-3-yl]methylene]-, (2Z)-
- CBNumber:
- CB22731159
- Molecular Formula:
- C23H24N2O
- Molecular Weight:
- 344.45
- MDL Number:
- MOL File:
- 929256-79-1.mol
Last updated:2024-10-23 13:36:13
VJ115 Chemical Properties,Uses,Production
Description
VJ115 is a novel chemical entity that inhibits the enzyme ENOX1, a NADH oxidase. Genetic and small molecule inhibition of ENOX1 inhibits endothelial cell tubule formation and tumor-mediated neo-angiogenesis. Inhibition of ENOX1 radiosensitizes tumor vasculature, a consequence of enhanced apoptosis. VJ115 inhibition of ENOX1 can impact expression of proteins involved in cytoskeletal reorganization and support a hypothesis in which ENOX1 activity links elevated cellular NADH concentrations with cytoskeletal reorganization and angiogenesis.
VJ115 Preparation Products And Raw materials
Raw materials
Preparation Products
VJ115 Suppliers
Global( 2)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19863 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19711 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
VJ115
1-Azabicyclo[2.2.2]octan-3-ol, 2-[[1-(phenylmethyl)-1H-indol-3-yl]methylene]-, (2Z)-
929256-79-1