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4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol

CAS No.
681482-81-5
Chemical Name:
4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol
Synonyms
Delamanid Impurity 4;Delamani intermediate;Delamanid Phenol Impurity;4-{4-[4-(Trifluoromethoxy)phenoxy]piperidino}benzenol;4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol;Phenol, 4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]-
CBNumber:
CB22734837
Molecular Formula:
C18H18F3NO3
Molecular Weight:
353.34
MDL Number:
MFCD16170437
MOL File:
681482-81-5.mol
Last updated:2023-04-23 13:52:06

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Properties

Melting point 113-114°C
Boiling point 461.2±45.0 °C(Predicted)
Density 1.308±0.06 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka 12.25±0.30(Predicted)
form Solid
color Beige

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T790895 4-[4-(4-Trifluoromethoxyphenoxy)piperidin-1-yl]phenol 681482-81-5 5mg $150 2021-12-16 Buy
TRC T790895 4-[4-(4-Trifluoromethoxyphenoxy)piperidin-1-yl]phenol 681482-81-5 25mg $575 2021-12-16 Buy
Matrix Scientific 169295 4-{4-[4-(Trifluoromethoxy)phenoxy]piperidino}benzenol 681482-81-5 500mg $918 2021-12-16 Buy
Medical Isotopes, Inc. 49060 4-[4-(4-Trifluoromethoxyphenoxy)piperidin-1-yl]phenol 681482-81-5 25mg $1075 2021-12-16 Buy
Matrix Scientific 169295 4-{4-[4-(Trifluoromethoxy)phenoxy]piperidino}benzenol 681482-81-5 1g $1836 2021-12-16 Buy
Product number Packaging Price Buy
T790895 5mg $150 Buy
T790895 25mg $575 Buy
169295 500mg $918 Buy
49060 25mg $1075 Buy
169295 1g $1836 Buy

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Chemical Properties,Uses,Production

Uses

4-[4-(4-Trifluoromethoxyphenoxy)piperidin-1-yl]phenol is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Preparation Products And Raw materials

Raw materials

Preparation Products

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32760 60
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 7287 58
WinWin Chemical CO., Limited
+86-0577-64498589 +8615325081899 sales@win-winchemical.com China 14198 58
Changzhou Guiding Bio-Tech. Co.,Ltd.
+86-519-519-86686860 +8618795626222 ning@guiding-bio.com China 299 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131980 58
Suzhou Haoyi Biotechnology Technology Co., Ltd. 15995756885 15995756885@139.com China 45 58
ZHIWE CHEMTECH CO LTD 021-20221225 13917446399 sales@zhiwe.net China 616 61
Pharmavoyager 15351203386 2592141051@qq.com China 93 55
Tongling HengYou Biotechnology Co., Ltd. 021-50426030 13856289449 2630597085@qq.com China 1889 55
4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Phenol, 4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]- 4-{4-[4-(Trifluoromethoxy)phenoxy]piperidino}benzenol Delamanid Phenol Impurity Delamani intermediate Delamanid Impurity 4 681482-81-5