Terazosin
- CAS No.
- 63590-64-7
- Chemical Name:
- Terazosin
- Synonyms
- Urodie;HYTRIN;erazosin;arbonyl)-;Terazosin;terazosine;CID 663211;TERAZOSIN HCL;Vasomet：Vicard;Hytrin：Hytrinex
- CBNumber:
- CB2285511
- Molecular Formula:
- C19H25N5O4
- Molecular Weight:
- 387.43
- MDL Number:
- MFCD00072144
- MOL File:
- 63590-64-7.mol
- MSDS File:
- SDS
| Melting point | 281-283°C |
|---|---|
| Boiling point | 664.5±65.0 °C(Predicted) |
| Density | 1.332±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | H2O: 25 mg/mL |
| pka | pKa (0.1N NaOH): 7.1(at 25℃) |
| form | powder |
| color | white to off-white |
| Water Solubility | 30.6mg/L(22.5 ºC) |
| BCS Class | 1/3 |
| InChIKey | VCKUSRYTPJJLNI-UHFFFAOYSA-N |
| CAS DataBase Reference | 63590-64-7(CAS DataBase Reference) |
| NCI Dictionary of Cancer Terms | Hytrin |
| FDA UNII | 8L5014XET7 |
| ATC code | G04CA03 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P301+P312+P330 |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | TK8044925 |
Terazosin price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 466982 | Terazosin | 63590-64-7 | 1mg | $460 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA28036 | 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonxyl]piperazine hydrochloride | 63590-64-7 | 100g | $500 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005881 | TERAZOSIN 95.00% | 63590-64-7 | 1G | $693 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 13666 | TerazosinHCl | 63590-64-7 | 1g | $850 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA28036 | 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonxyl]piperazine hydrochloride | 63590-64-7 | 5G | $100 | 2021-12-16 | Buy |
Terazosin Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Crystalline Powder
Uses
Terazosin is used for the same indications as is prazosin; however, it has the advantage of being able to be used once a day.
Uses
An α-1-adrenergicblocker related to prazosin.
Uses
An a-1-adrenergicblocker related to prazosin
Definition
ChEBI: Terazosin is a member of quinazolines, a member of piperazines, a member of furans and a primary amino compound. It has a role as an antineoplastic agent, an antihypertensive agent and an alpha-adrenergic antagonist.
Clinical Use
Alpha-adrenoceptor blocker:
Hypertension
Benign prostatic hyperplasia (BPH)
Synthesis
Terazosin, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)- piperazine (12.2.13), only differs from prazosin in that the furyl radical is replaced with a tetrahydrofuryl radical. It is synthesized in exactly the same manner except using 1-(2-tetrahydrofuroyl)piperazine instead of 1-(2-furoyl)piperazine [48–51].
Drug interactions
Potentially hazardous interactions with other drugs
Anaesthetics: enhanced hypotensive effect.
Antidepressants: enhanced hypotensive effect with
MAOIs.
Avanafil, vardenafil, sildenafil and tadalafil: enhanced
hypotensive effect - avoid concomitant use.
Beta-blockers: enhanced hypotensive effect;
increased risk of first dose hypotensive effect.
Calcium-channel blockers: enhanced hypotensive
effect; increased risk of first dose hypotensive effect.
Diuretics: enhanced hypotensive effect; increased
risk of first dose hypotensive effect.
Moxisylyte: possibly severe postural hypotension
when used in combination.
Metabolism
Terazosin is metabolised in the liver; one of the
metabolites has antihypertensive activity.
Terazosin is excreted in faeces via the bile, and in the
urine, as unchanged drug and metabolites.
Terazosin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hebei shuoxi biotechnology co. LTD | +8613081092107 | CHINA | 964 | 58 | |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7724 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15354 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9314 | 58 |
| Hong Kong Tiansheng New Material Trading Co., Ltd | +8617320695765 | zxx@hktiansheng.com | China | 973 | 58 |
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | mack@tongyon.com | China | 2994 | 58 |
View Lastest Price from Terazosin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | Terazosin
63590-64-7
|
US $1520.00-1980.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2022-02-25 | Terazosin
63590-64-7
|
US $999.00 / KG | 1KG | 99% | 1 ton | Hong Kong Tiansheng New Material Trading Co., Ltd | |
 |
2022-02-25 | Terazosin
63590-64-7
|
US $19.99 / KG | 1KG | 99% | 20KG | Hong Kong Tiansheng New Material Trading Co., Ltd |
63590-64-7(Terazosin)Related Search:
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1-(4-Amino-6,7-dimethoxyquinazolin-2-yl)-4-[(tetrahydrofuran-2-yl)carbonyl]piperazine Methanone,[4-(4-aMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)- [4-(4-AMINO-6,7-DIMETHOXY-QUINAZOLIN-2-YL)PIPERAZIN-1-YL]-OXOLAN-2-YL-METHANONE 1-(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)-4-[(TETRAHYDRO-2-FURANYL)CARBONXYL]PIPERAZINE, HYDROCHLORIDE HYTRIN TERAZOSIN MONOHYDROCHLORIDE TERAZOSIN HCL 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)p arbonyl)- terazosine 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]- (9CI) 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)4-[(tetrahydro-2-furanyl)carbonyl]piperazine 6,7-Dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride Terazosin N-(2-tertrahydrofuroyl)-piperazine 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl) carbonxyl] piperazine hydrochloride [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-[(2S)-2-oxolanyl]methanone erazosin Terazosin USP/EP/BP 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-{(tetnaphydro-2-furanyl)carbonyl}piperazine CID 663211 63590-64-7 C19H26ClN5O4 C19H28ClN5O6 C19H25N5O4 C19H29ClN5O6 API's API Terazosin Intermediates & Fine Chemicals Pharmaceuticals