TCS HDAC6 20b
- CAS No.
- 956154-63-5
- Chemical Name:
- TCS HDAC6 20b
- Synonyms
- TCS HDAC6 20b;DQZMLPMCOMRJOR-MOVGKWKRSA-N;S-[(6S)-7-(1-adamantylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]-7-oxoheptyl] 2-methylpropanethioate;2-Methylpropanethioic acid-S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester;Propanethioic acid, 2-methyl-, S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester
- CBNumber:
- CB23037557
- Molecular Formula:
- C26H44N2O4S
- Molecular Weight:
- 480.7
- MDL Number:
- MFCD26792580
- MOL File:
- 956154-63-5.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
TCS HDAC6 20b price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 14977 | TCS HDAC6 20b ≥95% | 956154-63-5 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 14977 | TCS HDAC6 20b ≥95% | 956154-63-5 | 5mg | $145 | 2024-03-01 | Buy |
| Tocris | 4805 | TCSHDAC620b ≥98%(HPLC) | 956154-63-5 | 10 | $224 | 2021-12-16 | Buy |
| Usbiological | 256885 | TCS HDAC6 20b | 956154-63-5 | 10mg | $480 | 2021-12-16 | Buy |
| TRC | T012700 | TCSHDAC620b | 956154-63-5 | 25mg | $1260 | 2021-12-16 | Buy |
TCS HDAC6 20b Chemical Properties,Uses,Production
Description
TCS HDAC6 20b is an inhibitor of histone deacetylase 6 (HDAC6) that inhibits the growth of HCT116 cells synergistically when used at a concentration of 5 μM in combination with paclitaxel , but it has no activity on cell growth in HCT116 cells when used alone. It inhibits cell growth of α-positive MCF-7 breast cancer cells treated with estrogen but not untreated cells.
Uses
TCS HDAC6 20b is a histone deacetylase 6 (HDAC6)-selective inhibitor.
References
[1]. suzuki t, kouketsu a, itoh y, et al. highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. j med chem, 2006, 49(16): 4809-4812.
[2]. itoh y, suzuki t, kouketsu a, et al. design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. j med chem, 2007, 50(22): 5425-5438.
TCS HDAC6 20b Preparation Products And Raw materials
Raw materials
Preparation Products
TCS HDAC6 20b Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30253 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| Absin Bioscience Inc. | 021-38015121 15000105423 | chenjw@absin.cn | China | 24734 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| InvivoChem | 13549236410 | sales@invivochem.cn | China | 6749 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8739 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |
| Supplier | Advantage |
|---|---|
| Career Henan Chemica Co | 58 |
| EMMX Biotechnology LLC | 60 |
| BOC Sciences | 65 |
| Absin Bioscience Inc. | 58 |
| MedBioPharmaceutical Technology Inc | 58 |
| InvivoChem | 58 |
| TargetMol Chemicals Inc. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| ApexBio Technology | 58 |